Oral Pathology: Clinical Pathologic Correlations

Höfundar: Joseph A. Regezi; James Sciubba; Richard C. K. Jordan (Útgáfa: 7)
Oral Pathology: Clinical Pathologic Correlations

Kaup valmöguleikar

Diagnose oral diseases quickly and accurately! Oral Pathology: Clinical Pathologic Correlations, 7th Edition presents diseases and conditions by appearance and presentation, so that you can easily identify and plan treatment for common oral and paraoral problems. An atlas-style overview of pathologic conditions opens the book, and then each chapter describes pathologies in detail — depicting each with full-color clinical photos and photomicrographs.

In addition to covering the latest advances in oral pathology, this edition includes new radiographic images demonstrating advanced imaging techniques. Expert educators Joseph Regezi, James Sciubba, and Richard Jordan provide a quick reference that’s ideal for the lab, NBDE review, or chairside use! Organization of oral and maxillofacial diseases by clinical appearance — such as red-blue lesions or pigmented lesions — matches what you would expect to see upon a patient’s presentation, and provides a practical tool for developing differential diagnoses and planning treatment.

Nearly 1,000 full-color clinical photographs, photomicrographs, radiographs, and drawings help you learn to identify lesions and disease states. An atlas-style Clinical Overview section makes it easy to find key information, with one page showing clinical photos of common conditions and the facing page listing symptoms, causes, and significance. Nearly 200 summary boxes and tables offer clear, at-a-glance information on the clinical features, diagnosis, and treatment for many conditions.

Correlation of histopathology with clinical features of oral diseases assists the clinician in recognizing specific conditions and developing differential diagnoses and rational treatment approaches. Student resources on an Evolve companion website include 30 case studies, interactive lecture modules, and a 150-question practice exam to prepare you for the NBDE and for clinical practice. UPDATED content reflects current information and the latest advances in oral and maxillofacial pathology.

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Útgefandi
Elsevier Health Sciences (US)
ISBN
9780323297691
Print ISBN
9780323297684
Format
ePub
Útgáfa
7
Höfundar
Joseph A. Regezi; James Sciubba; Richard C. K. Jordan
Tungumál
English
Útgefið
2015-12-24
Prent takmörkun á líftíma
10

Kaflar

  • Oral Pathology
  • Cover
  • Front Matter
  • Oral Pathology
  • Table of Contents
  • Evolve
  • Copyright
  • Dedication
  • Contributors
  • Preface/Acknowledgments
  • What is the benefit of this presentation?
  • Key features
  • Evolve resources
  • Student
  • Instructor
  • Acknowledgments
  • List of Illustrations
  • List of Tables
  • Clinical overview
  • Chapter outline
  • Mucosal (surface) lesions
  • Vesiculobullous diseases
  • Ulcerative conditions
  • White lesions
  • Red-blue lesions
  • Pigmented lesions
  • Verrucal-papillary lesions
  • Submucosal swelling (by region)
  • Gingival swellings
  • Floor-of-mouth swellings
  • Lips and buccal mucosal swellings
  • Tongue swellings
  • Palatal swellings
  • Neck swellings
  • Differential diagnosis approach to jaw lesions
  • Cysts of the jaws and neck
  • Odontogenic tumors
  • Benign nonodontogenic tumors
  • Inflammatory jaw lesions
  • Malignancies of the jaws
  • Metabolic and genetic diseases
  • 1 : Vesiculobullous diseases
  • Chapter outline
  • Viral disease
  • Herpes simplex infection
  • Etiology and pathogenesis
  • Clinical features
  • Primary herpetic gingivostomatitis.
  • Clinical features
  • Treatment
  • Secondary, or recurrent, herpes simplex infection.
  • Etiology
  • Clinical features
  • Treatment
  • Differential diagnosis
  • Immunodeficiency.
  • Herpetic whitlow.
  • Histopathology.
  • Differential diagnosis.
  • Diagnosis.
  • Treatment.
  • Varicella-zoster infection
  • Primary disease (varicella, chickenpox)
  • Secondary disease (zoster, shingles)
  • Pathogenesis
  • Varicella.
  • Herpes zoster.
  • Clinical features
  • Varicella.
  • Herpes zoster.
  • Histopathology.
  • Differential diagnosis.
  • Treatment.
  • Hand-foot-and-mouth disease
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Herpangina
  • Etiology and pathogenesis
  • Clinical features
  • Differential diagnosis
  • Treatment
  • Measles (rubeola)
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Diagnosis
  • Treatment.
  • Immunologic disease
  • Pemphigus vulgaris
  • Etiology and pathogenesis
  • Clinical features
  • Etiology
  • Clinical features
  • Treatment
  • Histopathology and immunopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Topical steroids.
  • Systemic steroids.
  • Mucous membrane pemphigoid
  • Etiology and pathogenesis
  • Clinical features
  • Etiology
  • Clincial features
  • Treatment
  • Histopathology and immunopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Bullous pemphigoid
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology and immunopathology
  • Treatment
  • Dermatitis herpetiformis
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology and immunopathology
  • Treatment and prognosis
  • Linear immunoglobulin a bullous disease (LAD)
  • Hereditary disease
  • Epidermolysis bullosa
  • Etiology and pathogenesis
  • Clinical features
  • Treatment and prognosis
  • Bibliography
  • Viral disease
  • Immunologic and hereditary disease
  • 2 : Ulcerative conditions
  • Chapter outline
  • Reactive lesions
  • Traumatic ulcerations
  • Etiology
  • Clinical features
  • Acute ulcer
  • Chronic ulcer
  • Histopathology
  • Diagnosis
  • Treatment
  • Bacterial infections
  • Syphilis
  • Etiology and pathogenesis
  • Acquired syphilis
  • Early
  • Late
  • Congenital syphilis
  • Early
  • Late
  • Clinical features
  • Cause
  • Clinical features
  • Treatment
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Gonorrhea
  • Etiology
  • Clinical features
  • Differential diagnosis
  • Treatment
  • Tuberculosis
  • Etiology and pathogenesis
  • Clinical features
  • Etiology
  • Clinical features
  • Histopathology
  • Treatment
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Leprosy
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Diagnosis
  • Treatment
  • Actinomycosis
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Noma
  • Etiology and pathogenesis
  • Clinical features
  • Treatment
  • Fungal infections
  • Deep fungal infections
  • Etiology and pathogenesis
  • Pathogenesis
  • Symptoms
  • Primary site
  • Oral lesions
  • Microscopy
  • Treatment
  • Clinical features
  • Types
  • Clinical features
  • Diagnosis
  • Treatment
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Subcutaneous fungal infection: Sporotrichosis
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Diagnosis
  • Treatment
  • Opportunistic fungal infections: Mucormycosis (phycomycosis) and aspergillosis
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Immunologic diseases
  • Aphthous ulcers
  • Etiology
  • Immunologic disorder
  • Neurogenic inflammation
  • Mucosal healing defect
  • Microbiological
  • Nutritional deficiency
  • Chemical
  • Clinical features
  • Minor aphthous ulcers
  • Major aphthous ulcers
  • Herpetiform aphthous ulcers
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Antibiotics.
  • Other drugs.
  • Chronic ulcerative stomatitis
  • Behçet’s syndrome
  • Etiology
  • Clinical features
  • Etiology
  • Organs affected
  • Treatment
  • Histopathology
  • Diagnosis
  • Treatment
  • Reiter’s syndrome
  • Etiology
  • Clinical features
  • Diagnosis
  • Treatment
  • Erythema multiforme
  • Etiology and pathogenesis
  • Clinical features
  • Etiology
  • Clinical features
  • Treatment
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Drug reactions
  • Etiology and pathogenesis
  • Analgesics
  • Antibiotics
  • Anticonvulsants
  • Antifungals
  • Anti-inflammatory
  • Antimalarial
  • Cardiovascular
  • Psychotherapeutic
  • Other
  • Hyperimmune response (allergy)
  • Mediated by:
  • Nonimmunologic response (not ab dependent)
  • Clinical features
  • Histopathology
  • Diagnosis
  • Treatment
  • Contact allergies
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Diagnosis
  • Treatment
  • Wegener’s granulomatosis (granulomatosis with polyangiitis)
  • Etiology
  • Clinical features
  • Histopathology
  • Diagnosis
  • Treatment
  • Midline granuloma
  • Clinical features
  • Histopathology
  • Treatment
  • Chronic granulomatous disease
  • Cyclic neutropenia
  • Neoplasms
  • Squamous cell carcinoma of the oral cavity
  • Etiology
  • Pathogenesis
  • Clinical features
  • Carcinoma of the lips.
  • Carcinoma of the tongue.
  • Carcinoma of the floor of the mouth.
  • Carcinoma of the buccal mucosa and gingiva.
  • Carcinoma of the palate.
  • Histopathology
  • Differential diagnosis
  • Surgical management of squamous cell carcinoma of the oral cavity
  • Radiotherapy management of squamous cell carcinoma of the oral cavity
  • Clinical evaluation
  • Primary radiotherapy.
  • Conventional (standard) dose-fractionation schedules.
  • Nonconventional (altered) fractionation schedules.
  • Concurrent chemotherapy (chemoradiation).
  • Combined surgery and radiotherapy.
  • Adjuvant radiotherapy.
  • Adjuvant chemotherapy in combination with radiotherapy.
  • Molecular targeted agents in combination with radiation.
  • Palliative radiotherapy.
  • Therapeutic radiation complications.
  • Temporary side effects
  • Permanent side effects
  • Prognosis.
  • T—tumor
  • N—nodes
  • M—metastasis
  • Carcinoma of the maxillary sinus
  • Etiology
  • Clinical features
  • Histopathology
  • Diagnosis
  • Treatment and prognosis
  • Basal cell carcinoma of the skin
  • Clinical features
  • Histopathology
  • Treatment
  • Squamous cell carcinoma of the skin
  • Clinical features
  • Histopathology
  • Treatment
  • Bibliography
  • Infectious diseases
  • Immunologic diseases
  • Neoplasms
  • 3 : White lesions
  • Chapter outline
  • Hereditary conditions
  • Leukoedema
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • White sponge nevus (Cannon’s disease)
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Hereditary benign intraepithelial dyskeratosis
  • Etiology
  • Clinical features
  • Histopathology
  • Treatment
  • Follicular keratosis (Darier’s disease)
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Treatment and prognosis
  • Reactive lesions
  • Focal (frictional) hyperkeratosis
  • Etiology
  • Clinical features
  • Histopathology
  • Diagnosis
  • Treatment
  • White lesions associated with smokeless tobacco
  • Etiology
  • Clinical features
  • Etiology
  • Clinical features
  • Treatment
  • Histopathology
  • Treatment and prognosis
  • Nicotine stomatitis
  • Etiology
  • Clinical features
  • Etiology
  • Clinical features
  • Treatment
  • Histopathology
  • Treatment and prognosis
  • Hairy leukoplakia
  • Etiology and pathogenesis
  • Infections
  • Neoplasms
  • Other
  • Clinical features
  • Etiology
  • Clinical features
  • Treatment
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Hairy tongue (black hairy tongue)
  • Etiology
  • Clinical features
  • Etiology
  • Initiating factors
  • Clinical features
  • Treatment
  • Histopathology
  • Diagnosis
  • Treatment and prognosis
  • Dentifrice-associated slough
  • Preneoplastic and neoplastic lesions
  • Actinic cheilitis
  • Etiology and pathogenesis
  • Clinical features
  • Etiology
  • Clinical features
  • Treatment
  • Histopathology
  • Treatment
  • Actinic keratoses (solar keratoses)
  • Idiopathic leukoplakia
  • Etiology and pathogenesis
  • Clinical features
  • Risk factors
  • Sites of occurrence
  • High-risk sites for malignant transformation
  • Age
  • Microscopic diagnoses at first diagnosis
  • Transformation rates
  • Histopathology
  • Epithelial architecture
  • Cytologic atypia
  • Differential diagnosis
  • Treatment and prognosis
  • Other white lesions
  • Geographic tongue
  • Etiology
  • Clinical features
  • Etiology
  • Clinical features
  • Treatment
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Lichen planus
  • Etiology and pathogenesis
  • Clinical features
  • Cause
  • Clinical features
  • Possible risk of carcinoma
  • Pathology
  • Treatment
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Lupus erythematosus
  • Etiology and pathogenesis
  • Clinical features
  • Discoid lupus erythematosus.
  • Systemic lupus erythematosus.
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Nonepithelial white-yellow lesions
  • Candidiasis
  • Synonyms
  • Cause
  • Types
  • Etiology and pathogenesis
  • Clinical features
  • Acute
  • Chronic
  • Mucocutaneous
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Topical
  • Systemic
  • Mucosal burns
  • Etiology
  • Clinical features
  • Histopathology
  • Treatment
  • Submucous fibrosis
  • Etiology
  • Clinical features
  • Histopathology
  • Treatment and prognosis
  • Fordyce’s granules
  • Ectopic lymphoid tissue
  • Gingival cysts
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Treatment
  • Parulis
  • Lipoma
  • Bibliography
  • Hereditary conditions
  • Reactive lesions
  • Preneoplastic and neoplastic lesions
  • Other white lesions
  • Nonepithelial white-yellow lesions
  • 4 : Red-blue lesions
  • Chapter outline
  • Intravascular lesions
  • Congenital vascular anomalies
  • Congenital hemangiomas and congenital vascular malformations
  • Etiology
  • Clinical features
  • Histopathology
  • Diagnosis
  • Treatment
  • Encephalotrigeminal angiomatosis (Sturge-Weber syndrome)
  • Hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber syndrome)
  • Reactive lesions
  • Varix and other acquired vascular malformations
  • Pyogenic granuloma
  • Etiology
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Peripheral giant cell granuloma
  • Etiology
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Scarlet fever
  • Neoplasms
  • Erythroplakia
  • Etiology
  • Clinical features
  • Idiopathic mucosal red patch
  • Histopathology
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Kaposi sarcoma
  • Etiology’s
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Metabolic-endocrine conditions
  • Vitamin B deficiencies
  • Etiology
  • Clinical features
  • Diagnosis and treatment
  • Pernicious anemia
  • Etiology
  • Clinical features
  • Diagnosis
  • Treatment
  • Iron deficiency anemia
  • Etiology
  • Clinical features
  • Diagnosis
  • Treatment
  • Burning mouth syndrome
  • Etiology
  • Clinical features
  • Histopathology
  • Diagnosis
  • Treatment
  • Other oral-facial pain conditions
  • Trigeminal neuralgia
  • Glossopharyngeal neuralgia
  • Postherpetic neuralgia
  • Giant cell arteritis (temporal arteritis)
  • Atypical facial pain
  • Atypical odontalgia
  • Immunologic abnormalities
  • Plasma cell gingivitis
  • Etiology
  • Clinical features
  • Histopathology
  • Treatment
  • Drug reactions and contact allergies
  • Extravascular lesions
  • Petechiae and ecchymoses
  • Etiology
  • Clinical features
  • Diagnosis
  • Bibliography
  • 5 : Pigmented lesions
  • Chapter outline
  • Melanocytic lesions
  • Physiologic (ethnic) pigmentation
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Smoking-associated melanosis
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Oral melanotic macule
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Café-au-lait macules
  • Pigmented neuroectodermal tumor of infancy
  • Etiology
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Melanocytic nevus
  • Etiology
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Melanoacanthoma
  • Melanoma
  • Cutaneous melanoma
  • Oral melanoma
  • Biological subtypes
  • Etiology
  • Immunohistochemistry
  • Differential diagnosis
  • Treatment and prognosis
  • Nonmelanocytic lesions
  • Amalgam tattoo (focal argyrosis)
  • Etiology
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Drug-induced pigmentations
  • Heavy-metal pigmentations
  • Etiology
  • Clinical features
  • Significance
  • Bibliography
  • 6 : Verrucal-papillary lesions
  • Chapter outline
  • Reactive/infectious lesions
  • Squamous papilloma/oral wart
  • Etiology
  • Clinical features
  • Histopathology
  • Dysplastic oral warts
  • Differential diagnosis
  • Treatment and prognosis
  • Papillary hyperplasia
  • Etiology
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Condyloma latum
  • Condyloma acuminatum
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Focal epithelial hyperplasia
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Neoplasms
  • Keratoacanthoma
  • Etiology
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Verrucous carcinoma
  • Etiology
  • Etiology
  • Clinical features
  • Microscopy
  • Treatment
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Etiology
  • Clinical features
  • Treatment and prognosis
  • Idiopathic lesions
  • Pyostomatitis vegetans
  • Clinical features
  • Histopathology
  • Treatment and prognosis
  • Verruciform xanthoma
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Bibliography
  • Squamous papilloma/oral verruca vulgaris
  • Papillary hyperplasia
  • Condyloma acuminatum
  • Focal epithelial hyperplasia
  • Keratoacanthoma
  • Verrucous carcinoma
  • Pyostomatitis vegetans
  • Verruciform xanthoma
  • 7 : Connective tissue lesions
  • Chapter outline
  • Fibrous lesions
  • Reactive hyperplasias
  • Peripheral fibroma
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Focal fibrous hyperplasia
  • Etiology
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Denture-induced fibrous hyperplasia
  • Etiology
  • Clinical features
  • Treatment
  • Generalized gingival hyperplasia
  • Etiology
  • Clinical features
  • Histopathology
  • Treatment
  • Neoplasms
  • Solitary fibrous tumor
  • Myxoma
  • Clinical features
  • Histopathology
  • Treatment
  • Nasopharyngeal angiofibroma
  • Clinical features
  • Histopathology
  • Treatment
  • Nodular fasciitis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Myofibroblastic tumors
  • Clinical features
  • Histopathology
  • Treatment
  • Fibromatosis
  • Clinical features
  • Histopathology
  • Treatment
  • Fibrosarcoma
  • Clinical features
  • Histopathology
  • Treatment
  • Synovial sarcoma
  • Fibrohistiocytic tumors
  • Benign fibrous histiocytoma
  • Clinical features
  • Histopathology
  • Treatment
  • Malignant fibrous histiocytoma (pleomorphic undifferentiated sarcoma)
  • Clinical features
  • Histopathology
  • Treatment
  • Vascular lesions
  • Reactive lesions and congenital lesions
  • Lymphangioma
  • Etiology
  • Clinical features
  • Histopathology
  • Treatment
  • Neoplasms
  • Hemangiopericytoma
  • Angiosarcoma
  • Neural lesions
  • Reactive lesions
  • Traumatic neuroma
  • Etiology
  • Clinical features
  • Histopathology
  • Treatment
  • Neoplasms
  • Granular cell tumors
  • Etiology
  • Clinical features
  • Clinical features
  • Histopathology
  • Treatment
  • Clinical features
  • Histopathology
  • Treatment
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Schwannoma
  • Etiology
  • Clinical features
  • Histopathology
  • Treatment
  • Neurofibroma
  • Etiology
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Mucosal neuroma of multiple endocrine neoplasia syndrome type III
  • Etiology
  • Clinical features
  • Histopathology
  • Treatment
  • Palisaded encapsulated neuroma (solitary circumscribed neuroma)
  • Malignant peripheral nerve sheath tumor
  • Olfactory neuroblastoma
  • Muscle lesions
  • Reactive lesions
  • Myositis ossificans
  • Neoplasms
  • Leiomyoma and leiomyosarcoma
  • Rhabdomyoma and rhabdomyosarcoma
  • Fat lesions
  • Lipoma
  • Liposarcoma
  • Bibliography
  • Fibrous connective tissue lesions
  • Neural lesions
  • Muscle and fat lesions
  • 8 : Salivary gland diseases
  • Chapter outline
  • Reactive lesions
  • Mucus extravasation phenomenon
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Mucus retention cyst (obstructive sialadenitis)
  • Etiology and pathogenesis
  • Etiology
  • Clinical features
  • Treatment
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Maxillary sinus mucocoele (retention cyst and pseudocyst)
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Necrotizing sialometaplasia
  • Etiology
  • Clinical appearance
  • Clinical differential diagnosis
  • Treatment
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Adenomatoid hyperplasia
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Infectious sialadenitis
  • Mumps
  • Etiology and pathogenesis
  • Clinical features
  • Treatment and prognosis
  • Cytomegaloviral sialadenitis
  • Bacterial sialadenitis
  • Etiology and pathogenesis
  • Clinical features
  • Treatment and prognosis
  • Sarcoidosis
  • Etiology
  • Etiology
  • Clinical features
  • Diagnosis
  • Treatment
  • Clinical features
  • Histopathology
  • Diagnosis
  • Treatment and prognosis
  • Metabolic conditions
  • Sjögren’s syndrome
  • Etiology
  • Diagnosis
  • Treatment and prognosis
  • Etiology
  • Clinical features
  • Skin
  • Salivary and lacrimal glands
  • Gastrointestinal tract
  • Respiratory tract
  • Cardiovascular system
  • Musculoskeletal system
  • Hematopoietic system
  • Histopathology
  • Diagnosis
  • Treatment
  • Salivary lymphoepithelial lesion
  • Scleroderma
  • Clinical features
  • Histopathology
  • Treatment
  • Xerostomia
  • Etiology
  • Medications
  • Autoimmune or systemic diseases
  • Other conditions
  • Clinical features
  • Treatment
  • Palliation
  • Prescription strategies
  • Taste disturbances
  • Halitosis
  • Benign neoplasms
  • Mixed tumor (pleomorphic adenoma)
  • Clinical features
  • Clinical features
  • Histopathology
  • Treatment
  • Histopathology
  • Treatment and prognosis
  • Basal cell adenoma
  • Clinical features
  • Histopathology
  • Treatment and prognosis
  • Canalicular adenoma
  • Clinical features
  • Histopathology
  • Treatment and prognosis
  • Myoepithelioma
  • Oncocytic tumors
  • Oncocytoma
  • Papillary cystadenoma lymphomatosum (warthin’s tumor)
  • Sebaceous adenoma
  • Ductal papilloma
  • Malignant neoplasms
  • Low-grade malignancies
  • Intermediate-grade malignancies
  • High-grade malignancies
  • Clinical features
  • Histopathology
  • Treatment and prognosis
  • Mucoepidermoid carcinoma
  • Clinical features
  • Histopathology
  • Prognosis and treatment
  • Polymorphous low-grade adenocarcinoma
  • Clinical features
  • Minor salivary glands
  • Parotid gland
  • Submandibular gland
  • Nasal/nasopharynx
  • Histopathology
  • Treatment and prognosis
  • Adenoid cystic carcinoma
  • Clinical features
  • Histopathology
  • Treatment and prognosis
  • Clear cell carcinoma
  • Clear cell tumors
  • Clear cell change/artifact in other tumors
  • Acinic cell carcinoma
  • Clinical features
  • Histopathology
  • Treatment and prognosis
  • Adenocarcinoma not otherwise specified
  • Rare tumors
  • Carcinoma ex-mixed tumor/malignant mixed tumor/metastasizing mixed tumor
  • Epimyoepithelial carcinoma
  • Salivary duct carcinoma
  • Basal cell adenocarcinoma
  • Mammary analog secretory carcinoma (MASC)
  • Squamous cell carcinoma
  • Bibliography
  • Reactive lesions (noninfectious)
  • Infectious conditions
  • Conditions associated with immune defects
  • Xerostomia
  • Taste disturbances
  • Halitosis
  • Benign neoplasms
  • Malignant neoplasms
  • 9 : Lymphoid lesions
  • Chapter outline
  • Reactive lesions
  • Lymphoid hyperplasia
  • Epithelioid hemangioma (angiolymphoid hyperplasia with eosinophilia)
  • Etiology
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Developmental lesions
  • Lymphoepithelial cyst
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Neoplasms
  • Lymphoma
  • Non-Hodgkin’s lymphoma
  • Classification
  • Etiology
  • Staging
  • Subclassification
  • Clinical features
  • Treatment and prognosis
  • Specific lymphomas
  • Diffuse B-cell lymphoma
  • Follicular B-cell lymphoma
  • Extranodal marginal zone B-cell lymphoma
  • Mantle cell lymphoma
  • B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma
  • Burkitt’s lymphoma
  • Lymphomas associated with human immunodeficiency virus infection
  • Anaplastic large cell lymphoma
  • Natural killer/T-cell lymphoma, nasal type
  • Eosinophil-rich CD30-positive lymphoproliferative disorder
  • Hodgkin’s lymphoma
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Multiple myeloma/plasmacytoma
  • Leukemias
  • Acute leukemias
  • Chronic leukemias
  • Granulocytic sarcoma
  • Bibliography
  • Reactive lesions
  • Developmental lesions
  • Neoplasms
  • 10 : Cysts of the jaws and neck
  • Chapter outline
  • Odontogenic cysts
  • Periapical (radicular) cyst
  • Etiology and pathogenesis
  • Clinical features
  • Pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Lateral periodontal cyst
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Gingival cyst of the newborn
  • Dentigerous cyst
  • Etiology and pathogenesis
  • Clinical features
  • Clinical
  • Radiographic features
  • Histopathology
  • Possible complications
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Eruption cyst
  • Glandular odontogenic cyst
  • Clinical features
  • Clinical features
  • Histopathology
  • Behavior
  • Radiographic features
  • Histopathology
  • Treatment and prognosis
  • Odontogenic keratocyst/keratocystic odontogenic tumor
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Etiology
  • Clinical features
  • Calcifying odontogenic cyst (calcifying cystic odontogenic tumor)
  • Clinical features
  • Histopathology
  • Behavior
  • Variants
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Nonodontogenic cysts
  • Globulomaxillary cyst/lesion
  • Nasolabial cyst
  • Median mandibular cyst
  • Nasopalatine duct (incisive canal) cyst
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Pseudocysts
  • Aneurysmal bone cyst
  • Etiology
  • Clinical features
  • Histopathology
  • Treatment
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Traumatic (simple) bone cyst
  • Etiology
  • Clinical features
  • Treatment
  • Pathogenesis
  • Clinical features
  • Histopathology
  • Treatment and prognosis
  • Static bone cyst (Stafne’s bone defect)
  • Focal osteoporotic bone marrow defect
  • Soft tissue cysts of the neck
  • Branchial cyst/cervical lymphoepithelial cyst
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Dermoid cyst
  • Clinical features
  • Histopathology
  • Treatment
  • Thyroglossal tract cyst
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Bibliography
  • Odontogenic cysts
  • Nonodontogenic cysts
  • Cysts of the neck
  • 11 : Odontogenic tumors
  • Chapter outline
  • Benign, no recurrence potential
  • Benign, some recurrence potential
  • Benign aggressive
  • Malignant
  • Epithelial tumors
  • Ameloblastoma
  • Pathogenesis
  • Cell cycle–related factors
  • Interface factors (invasive properties enhanced)
  • Clinical features
  • Biological subtypes
  • Clinical features
  • Histopathology
  • Microscopic patterns
  • Treatment
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Calcifying epithelial odontogenic tumor (Pindborg tumor)
  • Histogenesis
  • Clinical features
  • Histopathology
  • Behavior
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Adenomatoid odontogenic tumor
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Squamous odontogenic tumor
  • Clear cell odontogenic tumor (carcinoma)
  • Histogenesis
  • Clinical features
  • Histopathology
  • Microscopic differential diagnosis
  • Behavior
  • Keratocystic odontogenic tumor (see odontogenic keratocyst/keratocystic odontogenic tumor in chapter 10 )
  • Dentinogenic ghost cell tumor (formerly calcifying odontogenic cyst)
  • Mesenchymal tumors
  • Odontogenic myxoma
  • Histogenesis
  • Clinical features
  • Histopathology
  • Microscopic differential diagnosis
  • Behavior
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Central odontogenic fibroma
  • Histogenesis
  • Clinical features
  • Histopathology
  • Microscopic differential diagnosis
  • Behavior
  • Cementifying fibroma
  • Cementoblastoma
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Periapical cemento-osseous dysplasia
  • Clinical features
  • Histopathology
  • Other
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Mixed (epithelial and mesenchymal) tumors
  • Ameloblastic fibroma and ameloblastic fibro-odontoma
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Odontoma
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Bibliography
  • 12 : Benign nonodontogenic tumors
  • Chapter outline
  • Ossifying fibroma
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Treatment
  • Clinical features
  • Juvenile trabecular ossifying fibroma
  • Juvenile psammomatoid ossifying fibroma
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Fibrous dysplasia
  • Clinical features
  • Histopathology
  • Treatment
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Cemento-osseous dysplasia
  • Osteoblastoma/osteoid osteoma
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Osteoma
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Desmoplastic fibroma
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Chondroma
  • Central giant cell granuloma
  • Clinical features
  • Histopathology
  • Treatment
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Hyperparathyroidism
  • Aneurysmal bone cyst
  • Cherubism
  • Treatment and prognosis
  • Giant cell tumor
  • Hemangioma of bone
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Langerhans cell disease
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Localized disease
  • Disseminated disease
  • Tori and exostoses
  • Etiology and pathogenesis
  • Clinical features
  • Torus palatinus
  • Torus mandibularis
  • Exostoses
  • Histopathology
  • Treatment and prognosis
  • Coronoid hyperplasia
  • Etiology and pathogenesis
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Bibliography
  • 13 : Inflammatory jaw lesions
  • Chapter outline
  • Pulpitis
  • Etiology
  • Clinical and histopathologic features
  • Focal reversible pulpitis.
  • Acute pulpitis.
  • Chronic pulpitis.
  • Chronic hyperplastic pulpitis.
  • Treatment and prognosis
  • Periapical abscess
  • Etiology
  • Clinical features
  • Inflammatory
  • Benign
  • Benign, aggressive
  • Malignant
  • Histopathology
  • Treatment and prognosis
  • Acute osteomyelitis
  • Etiology
  • Clinical features
  • Histopathology
  • Treatment
  • Chronic osteomyelitis (chronic osteitis)
  • Etiology
  • Definition
  • Clinical features
  • Histopathology
  • Osteoradionecrosis.
  • Clinical features
  • Histopathology
  • Treatment
  • Bisphosphonate-related osteonecrosis
  • Bisphosphonate description
  • Mechanisms of action
  • Benefits and risks of bisphosphonate therapy
  • Benefits
  • Risks
  • Bisphosphonate-related osteonecrosis of the jaws
  • Precipitating events and risk factors for jaw disease
  • Drug associated
  • Dental or local factors
  • Systemic factors
  • Treatment of bisphosphonate-related osteonecrosis of the jaws
  • Dental management of patients undergoing bisphosphonate therapy
  • Chronic osteomyelitis with proliferative periostitis (so-called Garré’s osteomyelitis)
  • Etiology
  • Clinical features
  • Histopathology
  • Treatment
  • Diffuse sclerosing osteomyelitis
  • Etiology
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Focal sclerosing osteitis
  • Etiology
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment
  • Bibliography
  • 14 : Malignancies of the jaws
  • Chapter outline
  • Osteosarcoma
  • Etiology
  • Clinical features
  • Histopathology
  • Treatment
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Management
  • Prognosis
  • Juxtacortical osteosarcoma
  • Parosteal osteosarcoma
  • Periosteal osteosarcoma
  • Chondrosarcoma
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Mesenchymal chondrosarcoma
  • Ewing’s sarcoma and primitive neuroectodermal tumor
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Burkitt’s lymphoma
  • Clinical features
  • Histopathology
  • Treatment and prognosis
  • Plasma cell neoplasms
  • Multiple myeloma
  • Origin
  • Clinical and laboratory features
  • Treatment
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Treatment and prognosis
  • Solitary plasmacytoma of bone
  • Metastatic carcinoma
  • Clinical features
  • Histopathology
  • Differential diagnosis
  • Osteonecrosis related to metastatic disease.
  • Treatment and prognosis
  • Bibliography
  • Osteosarcoma
  • Chondrosarcoma
  • Ewing’s sarcoma
  • Plasma cell neoplasms
  • Metastatic carcinoma
  • Osteonecrosis related to metastatic disease
  • 15 : Metabolic and genetic diseases
  • Chapter outline
  • Metabolic conditions
  • Paget’s disease
  • Clinical features
  • Histopathology
  • Treatment
  • Hyperparathyroidism
  • Clinical features
  • Histopathology
  • Treatment
  • Hyperthyroidism
  • Hypothyroidism
  • Hypophosphatasia
  • Infantile cortical hyperostosis
  • Phantom bone disease (Gorham’s disease)
  • Acromegaly
  • Etiology
  • Clinical features
  • Treatment
  • Genetic abnormalities
  • Cherubism
  • Clinical features
  • Histopathology
  • Treatment and prognosis
  • Osteopetrosis
  • Clinical features
  • Histopathology
  • Treatment and prognosis
  • Osteogenesis imperfecta
  • Clinical features
  • Treatment and prognosis
  • Cleidocranial dysplasia
  • Etiology and pathogenesis
  • Clinical features
  • Treatment
  • Crouzon’s syndrome (craniofacial dysostosis)
  • Etiology and pathogenesis
  • Clinical features
  • Treatment and prognosis
  • Treacher Collins syndrome (mandibulofacial dysostosis)
  • Etiology and pathogenesis
  • Clinical findings
  • Treatment and prognosis
  • Pierre Robin syndrome (Pierre Robin sequence)
  • Etiology and pathogenesis
  • Clinical features
  • Treatment and prognosis
  • Marfan’s syndrome
  • Etiology and pathogenesis
  • Clinical features
  • Treatment and prognosis
  • Ehlers-Danlos syndrome
  • Etiology and pathogenesis
  • Clinical features
  • Treatment and prognosis
  • Down syndrome (trisomy 21)
  • Etiology and pathogenesis
  • Clinical features
  • Treatment and prognosis
  • Hemifacial atrophy
  • Hemifacial hypertrophy
  • Etiology and pathogenesis
  • Clinical features
  • Differential diagnosis
  • Treatment and prognosis
  • Clefts of the lip and palate
  • Etiology and pathogenesis
  • Clinical features
  • Treatment and prognosis
  • Fragile X syndrome
  • Etiology and pathogenesis
  • Clinical features
  • Treatment and prognosis
  • Bibliography
  • Metabolic conditions
  • Genetic abnormalities
  • 16 : Abnormalities of teeth
  • Chapter outline
  • Alterations in size
  • Microdontia
  • Macrodontia
  • Alterations in shape
  • Gemination
  • Fusion
  • Concrescence
  • Dilaceration
  • Dens invaginatus
  • Dens evaginatus
  • Taurodontism
  • Supernumerary roots
  • Enamel pearls
  • Attrition, abrasion, erosion
  • Alterations in number
  • Anodontia
  • Etiology
  • Characteristic signs and symptoms
  • Impaction
  • Supernumerary teeth
  • Defects of enamel
  • Environmental defects of enamel
  • Amelogenesis imperfecta
  • Defects of dentin
  • Dentinogenesis imperfecta
  • Dentin dysplasia
  • Defects of enamel and dentin
  • Regional odontodysplasia
  • Abnormalities of dental pulp
  • Pulp calcification
  • Internal resorption
  • External resorption
  • Alterations in color
  • Exogenous stains
  • Endogenous stains
  • Bibliography
  • GENERIC-TITLE
  • Index
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  • I
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