Nuclear Medicine and Molecular Imaging

Höfundur: David Gilmore (Útgáfa: 9)
Nuclear Medicine and Molecular Imaging

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Master the latest imaging procedures and technologies in nuclear medicine! Nuclear Medicine and Molecular Imaging: Technology and Techniques, 9th Edition provides comprehensive, state-of-the-art information on all aspects of nuclear medicine. Coverage of body systems includes anatomy and physiology, along with details on how to perform and interpret related diagnostic procedures. The leading technologies — SPECT, PET, CT, MRI, and PET/CT — are presented with an emphasis on radiation safety and patient care.

Comprehensive coverage of nuclear medicine and molecular imaging makes this a complete resource. Accessible writing style simplifies topics, first introducing fundamentals and progressing to more complex concepts. Procedure boxes provide step-by-step instructions for clinical procedures and protocols so they can be performed with confidence. NEW! Full-color design provides clear and realistic examples of PET/CT scans seen in practice.

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Útgefandi
Elsevier Health Sciences (US)
ISBN
9780323763981
Print ISBN
9780323775502
Format
ePub
Útgáfa
9
Höfundar
David Gilmore
Tungumál
English
Útgefið
2022-08-22
Prent takmörkun á líftíma
10

Kaflar

  • Cover image
  • Title page
  • Table of Contents
  • Copyright
  • Contributors
  • Reviewers
  • Preface
  • Acknowledgments
  • List of Illustrations
  • List of Tables
  • Section 1. Foundations
  • 1.  Mathematics and statistics
  • Fundamentals
  • Practical applications
  • Statistics
  • Summary
  • Review questions
  • Acknowledgement
  • References
  • 2.  Cell and molecular biology
  • Eukaryotic cell structure
  • Control of gene expression
  • The cell cycle
  • Molecular basis of cancer
  • Summary
  • References
  • 3.  General chemistry and biochemistry
  • Elements, compounds, and mixtures
  • Laws of constant composition and multiple proportion
  • Atomic weights, molecular weights, and the mole concept
  • Solutions and colloids
  • Chemical reactions and equations
  • Double displacement reactions
  • Oxidation–reduction reactions
  • Electrolytic reactions
  • Acids and bases
  • Equilibriums and equilibrium constant
  • The pH concept
  • Buffer solutions
  • Organic compounds
  • Summary
  • Suggested reading
  • 4.  Radiochemistry and radiopharmacology
  • Production of radionuclides
  • Nuclear pharmacy
  • References
  • 5.  Radiation safety in nuclear medicine
  • Radiation safety program
  • Sources of radiation exposure
  • Radiation regulations
  • Radiation dose
  • Biological effects of ionizing radiation
  • Summary
  • Acknowledgement
  • References
  • Suggested reading
  • Section 2. Patient Care, Management, and Research
  • 6.  Patient care
  • Introduction to patient care
  • Diversity in health care
  • Socioeconomic challenges
  • Cultural competence
  • Health information and HIPAA
  • HIPAA overview
  • Patient care
  • Body mechanics
  • Medication administration
  • Contrast media
  • Infection control
  • Vital signs and patient assessment
  • Emergency care
  • Ancillary equipment
  • Summary
  • Acknowledgment
  • References
  • 7.  Department administration and clinical research
  • Health care leadership
  • Health care management
  • Coding and reimbursement
  • Quality measures and improvement
  • Accreditation
  • Clinical research
  • Clinical trials and studies
  • Conclusion
  • Summary
  • References
  • Suggested reading
  • 8.  Health informatics in imaging
  • Background
  • Computers in health care
  • Computer hardware
  • Computer software
  • Image acquisition
  • Image display and processing
  • Region of interest
  • Clinical applications
  • Health information systems
  • Electronic health records
  • Radiology information system
  • Standard operating procedures
  • Future advances
  • References
  • Suggested reading
  • Section 3. Physics and Instrumentation
  • 9.  Physics of nuclear medicine
  • Matter
  • Nucleus of an atom
  • Nature of electromagnetic radiation
  • Mass energy equivalence
  • Units
  • Modes of radioactive decay
  • Mathematics of decay
  • Units of radioactivity
  • Decay factor and precalibration factor
  • Effective half-life
  • Parent–daughter radionuclide relationships
  • Interaction with matter
  • Attenuation and transmission of photons
  • Summary
  • 10.  Instrumentation
  • Radiation detection
  • Gas-filled detectors
  • Gas ionization curve
  • Survey meters
  • Dose calibrator
  • Dose calibrator quality control
  • Scintillation detectors
  • Gamma cameras
  • Gamma camera detector components
  • Spectroscopy
  • Gamma camera corrections
  • Image acquisition
  • Single-photon emission computed tomography
  • Image quality
  • Gamma camera quality control
  • Scintillation counting systems
  • Summary
  • Acknowledgement
  • References
  • 11.  Computed tomography physics and instrumentation
  • Physics of x-rays
  • X-ray tube and the production of x-rays
  • Principles of computed tomography
  • Computed tomography scanner design
  • Multislice helical computed tomography systems
  • Image data acquisition
  • Computed tomography image reconstruction
  • Computed tomography display
  • Display of volumetric image data
  • Image quality
  • Computed tomography protocols
  • Computed tomography artifacts
  • Computed tomography radiation safety
  • Computed tomography quality control
  • Summary
  • Acknowledgement
  • Suggested reading
  • 12.  Positron emission tomography instrumentation
  • Physics of positrons
  • Production of positron emission tomography radiotracers
  • Coincidence detection in positron emission tomography
  • Positron emission tomography scintillation crystals
  • Time-of-flight positron emission tomography
  • Positron emission tomography scanner design
  • Data acquisition
  • Reconstruction algorithms
  • Attenuation correction
  • Displaying positron emission tomography data
  • Image fusion
  • Hybrid scanners
  • Scanner calibration and quality control
  • Partial-volume effect
  • Quantitative image information
  • Radiation safety in postron emssion tomography
  • Requirements for gating and radiation therapy treatment planning
  • Summary
  • Suggested reading
  • 13.  Principles of magnetic resonance imaging
  • History
  • Introduction to atomic structure and basic principles
  • Hydrogen nucleus
  • Precession
  • Resonance and excitation
  • Free induction decay
  • T1 and T2
  • Instrumentation
  • Pulse sequences and scan parameters
  • Contrast media
  • Safety
  • Hybrid imaging: Positron emission tomography/magnetic resonance imaging
  • Summary
  • Suggested readings
  • Section 4. Imaging Procedures and Protocols
  • 14.  Central nervous system
  • Anatomy and physiology
  • Chemistry of the brain
  • Blood supply
  • Radiopharmaceuticals
  • Imaging techniques and protocols
  • Clinical positron emission tomography and single-photon emission computed tomography studies
  • Summary
  • Acknowledgment
  • References
  • 15.  Endocrine system
  • Thyroid gland
  • Parathyroid glands
  • Neuroendocrine system
  • Adrenal glands
  • Summary
  • References
  • 16.  Respiratory system
  • Introduction and history
  • Normal anatomy and physiology
  • Pathophysiology
  • Radiopharmaceuticals
  • Perfusion imaging
  • Ventilation–perfusion studies
  • Interpretation
  • Summary
  • References
  • 17.  Cardiovascular system
  • Anatomy, physiology, and pathology
  • Myocardial perfusion imaging
  • Positron emission tomography of the heart
  • Radionuclide evaluation of ventricular function
  • Imaging cardiac neurotransmission
  • Summary
  • Acknowledgment
  • References
  • Suggested reading
  • 18.  Gastrointestinal system
  • Stomach
  • Small bowel and colon
  • Intestinal tract
  • Liver and spleen
  • Gallbladder
  • Summary
  • Acknolwledgment
  • References
  • Suggested reading
  • 19.  Genitourinary system
  • Anatomy
  • Physiology
  • Radiopharmaceuticals
  • Radionuclide procedures
  • Measurement of effective renal plasma flow and the glomerular filtration rate
  • Summary
  • References
  • 20.  Skeletal system
  • Composition of bone
  • Gross structure of bone
  • Joints
  • Radionuclide imaging
  • Instrumentation
  • Spot views
  • Whole-body imaging
  • Single-photon emission computed tomography imaging
  • Multiphase bone imaging
  • Clinical aspects
  • Other uses for bone imaging
  • Acknowledgements
  • Summary
  • References
  • Suggested reading
  • 21.  Clinical PET/CT in oncology
  • Fluorine-18 fluorodeoxyglucose
  • Fluorodeoxyglucose patient preparation and injection
  • Positron emission tomography scan acquisition
  • Normal fluorodeoxyglucose distribution
  • Normal variations in fluorodeoxyglucose localization
  • Fluorodeoxyglucose oncology applications
  • Gallium-68 DOTATATE (NETSPOT)
  • Radiopharmaceuticals
  • Positron emission tomography/computed tomography oncology future trends
  • Summary
  • Acknowledgement
  • References
  • Suggested reading
  • Section 5. A Summary of the More
  • 22.  Theranostics
  • Principles of theranostics
  • Theranostic radionuclides
  • Traditional theranostics in nuclear medicine
  • Recent and emerging theranostics in nuclear medicine and molecular imaging
  • Developments in theranostics
  • References
  • 23.  Supplementary procedures: Breast, lymph nodes, esophagus, salivary glands, inflammation, testicular, and the carbon-14 breath test
  • Tumor imaging for breast cancer
  • Esophagus
  • Salivary glands
  • Breath testing with carbon-14–labeled compounds
  • Inflammatory imaging
  • Testicular imaging
  • Summary
  • Acknowledgement
  • References
  • Appendix A: Percentage points and chi square distribution
  • Appendix B: Radionuclides and radiopharmaceutical forms used in clinical nuclear medicine (includes research radiopharmaceuticals)
  • Appendix C: Glossary
  • Appendix D: Answers to Chapter 1 Mathematics and Statistics review
  • Index