Medical Biotechnology

Höfundar: Bernard R. Glick; ‎Cheryl L. Patten; ‎Terry L. Delovitch (Útgáfa: 1)
Medical Biotechnology

Kaup valmöguleikar

The future is now--this groundbreaking textbook illustrates how biotechnology has radically changed the way we think about health care Biotechnology is delivering not only new products to diagnose, prevent, and treat human disease but entirely new approaches to a wide range of difficult biomedical challenges. Because of advances in biotechnology, hundreds of new therapeutic agents, diagnostic tests, and vaccines have been developed and are available in the marketplace.

In this jargon-free, easy-to-read textbook, the authors demystify the discipline of medical biotechnology and present a roadmap that provides a fundamental understanding of the wide-ranging approaches pursued by scientists to diagnose, prevent, and treat medical conditions. Medical Biotechnology is written to educate premed and medical students, dental students, pharmacists, optometrists, nurses, nutritionists, genetic counselors, hospital administrators, and individuals who are stakeholders in the understanding and advancement of biotechnology and its impact on the practice of modern medicine.

Nánar um bókina

Útgefandi
Wiley Global Research (STMS)
ISBN
9781683673477
Print ISBN
9781555817053
Format
ePub
Útgáfa
1
Höfundar
Bernard R. Glick; ‎Cheryl L. Patten; ‎Terry L. Delovitch
Tungumál
English
Útgefið
2013-12-02
Prent takmörkun á líftíma
100
Prent takmörkun
10
Afritunar takmörkun
2

Kaflar

  • Cover
  • Preface
  • About the Authors
  • SECTION I: The Biology behind the Technology
  • 1 Fundamental Technologies
  • Molecular Cloning
  • Genomic Libraries
  • Amplification of DNA Using PCR
  • DNA Sequencing Technologies
  • Sequencing Whole Genomes
  • Genomics
  • summary
  • review questions
  • references
  • 2 Fundamental Concepts in Immunology
  • The Immune Response
  • Functions of the Immune System
  • Cells of the Immune System: Cell-Mediated Immunity
  • Tissues of the Immune System
  • Humoral Immunity
  • Types of Antibodies: Applications
  • Immunological Techniques
  • summary
  • review questions
  • references
  • 3 The Genetic Basis of Disease
  • Chromosomal Disorders and Gene Mapping
  • Single-Gene Disorders
  • Polygenic Disorders and Gene Clustering
  • Mitochondrial Disorders
  • summary
  • review questions
  • references
  • 4 Immune Pathogenesis
  • Models of Immune System Lesions
  • Inflammation and Immune Hypersensitivity Disorders
  • Immunodeficiency Disorders and Defects in Development of the Immune System
  • summary
  • review questions
  • references
  • 5 Microbial Pathogenesis
  • Introduction
  • Bacterial Infections
  • Viral Infections
  • summary
  • review questions
  • references
  • SECTION II: Production of Therapeutic Agents
  • 6 Modulation of Gene Expression
  • Manipulating Gene Expression in Prokaryotes
  • Heterologous Protein Production in Eukaryotic Cells
  • Directed Mutagenesis
  • summary
  • review questions
  • references
  • 7 Genetic Engineering of Plants
  • Plant Transformation with the Ti Plasmid of A. tumefaciens
  • Physical Transfer of Genes to Plants
  • Chloroplast Engineering
  • Transient Gene Expression
  • Molecular Pharming
  • Edible Vaccines
  • summary
  • review questions
  • references
  • SECTION III: Diagnosing and Treating Human Disease
  • 8 Molecular Diagnostics
  • Immunological Approaches To Detect Protein Biomarkers of Disease
  • DNA-Based Approaches to Disease Diagnosis
  • Detecting RNA Signatures of Disease
  • summary
  • review questions
  • references
  • 9 Protein Therapeutics
  • Pharmaceuticals
  • Recombinant Antibodies
  • Enzymes
  • Lactic Acid Bacteria
  • summary
  • review questions
  • references
  • 10 Nucleic Acid Therapeutic Agents and Human Gene Therapy
  • Treating Genetic and Nongenetic Disorders
  • Targeting Specific mRNAs and DNAs
  • Viral Delivery Systems
  • Nonviral Nucleic Acid Delivery Systems
  • Gene Therapy
  • summary
  • review questions
  • references
  • 11 Vaccines
  • Vaccination: Overview
  • Subunit Vaccines
  • Peptide Vaccines
  • Dendritic Cell Vaccines
  • DNA Vaccines
  • Attenuated Vaccines
  • Vector Vaccines
  • Adjuvants
  • Systems Biology and Evaluation of Vaccines
  • summary
  • review questions
  • references
  • 12 Societal Issues
  • Safety and Ethical Issues
  • Patenting Biotechnology
  • Economic Issues
  • summary
  • review questions
  • references
  • Glossary
  • Index
  • End User License Agreement