Mechanics of Biomaterials

Höfundar: Lisa A. Pruitt; Ayyana M. Chakravartula (Útgáfa: 1)
Mechanics of Biomaterials

Kaup valmöguleikar

Teaching mechanical and structural biomaterials concepts for successful medical implant design, this self-contained text provides a complete grounding for students and newcomers to the field. Split into three sections: Materials, Mechanics and Case Studies, it begins with a review of sterilization, biocompatibility and foreign body response before presenting the fundamental structures of synthetic biomaterials and natural tissues.

Mechanical behavior of materials is then discussed in depth, covering elastic deformation, viscoelasticity and time-dependent behavior, multiaxial loading and complex stress states, yielding and failure theories, and fracture mechanics. The final section on clinical aspects of medical devices provides crucial information on FDA regulatory issues and presents case studies in four key clinical areas: orthopedics, cardiovascular devices, dentistry and soft tissue implants.

Nánar um bókina

Útgefandi
Cambridge University Press
ISBN
9781139124287
Print ISBN
9780521762212
Format
ePub
Útgáfa
1
Höfundar
Lisa A. Pruitt; Ayyana M. Chakravartula
Tungumál
English
Útgefið
2011-10-20
Prent takmörkun á líftíma
10
Prent takmörkun
5
Afritunar takmörkun
5

Kaflar

  • Coverpage
  • Halftitle page
  • CAMBRIDGE TEXTS IN BIOMEDICAL ENGINEERING
  • Title page
  • Copyright page
  • Contents
  • Symbols
  • Prologue
  • Part I Materials
  • 1 Biocompatibility, sterilization, and materials selection for implant design
  • 1.1 Historical perspective and overview
  • 1.2 Learning objectives
  • 1.3 Successful device performance and implant design
  • 1.4 Biocompatibility
  • 1.5 Sterility
  • 1.6 Regulatory issues
  • 1.7 Structural requirements
  • 1.8 Classifying biomaterials
  • 1.9 Structure-property relationships
  • 1.10 Attributes and limitations of synthetic biomaterials
  • 1.11 Case study: deterioration of orthopedic-grade UHMWPE due to ionizing radiation
  • 1.12 Summary
  • 1.13 Problems for consideration
  • 1.14 References
  • 2 Metals for medical implants
  • 2.1 Historical perspective and overview
  • 2.2 Learning objectives
  • 2.3 Bonding and crystal structure
  • 2.4 Interstitial sites
  • 2.5 Crystallographic planes and directions
  • 2.6 Theoretical shear strength
  • 2.7 Imperfections in metals and alloys
  • 2.8 Metal processing
  • 2.9 Corrosion processes
  • 2.10 Metals in medical implants
  • 2.11 Case study: corrosion in modular orthopedic implants
  • 2.12 Summary
  • 2.13 Problems for consideration
  • 2.14 References
  • 3 Ceramics
  • 3.1 Historical perspective and overview
  • 3.2 Learning objectives
  • 3.3 Bonding and crystal structure
  • 3.4 Mechanical behavior of ceramics
  • 3.5 Processing of ceramics
  • 3.6 Ceramics in medical implants
  • 3.7 Case study: the use of coral as a bone substitute
  • 3.8 Summary
  • 3.9 Problems for consideration
  • 3.10 References
  • 4 Polymers
  • 4.1 Historical perspective and overview
  • 4.2 Learning objectives
  • 4.3 Bonding and crystal structure
  • 4.4 Molecular weight distribution in polymers
  • 4.5 Mechanical behavior of polymers
  • 4.6 Polymer processing
  • 4.7 Polymers in medical implants
  • 4.8 Case study: resorbable sutures and suture anchors
  • 4.9 Summary
  • 4.10 Problems for consideration
  • 4.11 References
  • 5 Mechanical behavior of structural tissues
  • 5.1 Historical perspective and overview
  • 5.2 Learning objectives
  • 5.3 Building blocks of tissues
  • 5.4 Load-bearing tissues
  • 5.5 Case study: creating a scaffold for tissue engineering
  • 5.6 Summary
  • 5.7 Problems for consideration
  • 5.8 References
  • 5.9 Bibliography
  • Part II Mechanics
  • 6 Elasticity
  • 6.1 Overview
  • 6.2 Learning objectives
  • 6.3 Stress and strain
  • 6.4 Bending stresses and beam theory
  • 6.5 Composites
  • 6.6 Case study: modifying material and cross-section to reduce bone absorption
  • 6.7 Summary
  • 6.8 Problems for consideration
  • 6.9 References
  • 6.10 Bibliography
  • 7 Viscoelasticity
  • 7.1 Overview
  • 7.2 Learning objectives
  • 7.3 Introduction to viscoelasticity
  • 7.4 Linear viscoelastic networks
  • 7.5 Frequency domain analysis
  • 7.6 Time-temperature equivalence
  • 7.7 Nonlinear viscoelasticity
  • 7.8 Case study: creep behavior of UHMWPE used in total joint replacements
  • 7.9 Summary
  • 7.10 Problems for consideration
  • 7.11 References
  • 8 Failure theories
  • 8.1 Overview
  • 8.2 Learning objectives
  • 8.3 Yield surfaces
  • 8.4 Maximum shear stress (Tresca yield criterion)
  • 8.5 Maximum distortional energy (von Mises yield criterion)
  • 8.6 Predicting yield in multiaxial loading conditions
  • 8.7 Modified yield criteria
  • 8.8 Maximum normal stress failure theory
  • 8.9 Notches and stress concentrations
  • 8.10 Failure mechanisms in structural biomaterials
  • 8.11 Case study: stress distribution in a total joint replacement
  • 8.12 Summary
  • 8.13 Problems for consideration
  • 8.14 References
  • 9 Fracture mechanics
  • 9.1 Overview
  • 9.2 Learning objectives
  • 9.3 Linear elastic fracture mechanics (LEFM)
  • 9.4 Modified methods in LEFM
  • 9.5 Elastic-plastic fracture mechanics (EPFM)
  • 9.6 Time-dependent fracture mechanics (TDFM)
  • 9.7 Intrinsic and extrinsic fracture processes
  • 9.8 Fracture mechanisms in structural materials
  • 9.9 Case study: fracture of highly crosslinked acetabular liners
  • 9.10 Summary
  • 9.11 Problems for consideration
  • 9.12 References
  • 10 Fatigue
  • 10.1 Overview
  • 10.2 Learning objectives
  • 10.3 Fatigue terminology
  • 10.4 Total life philosophy
  • 10.5 Strain-based loading
  • 10.6 Marin factors
  • 10.7 Defect-tolerant philosophy
  • 10.8 Case study: fatigue fractures in trapezoidal hip stems
  • 10.9 Summary
  • 10.10 Problems for consideration
  • 10.11 References
  • 11 Friction, lubrication, and wear
  • 11.1 Overview
  • 11.2 Learning objectives
  • 11.3 Bulk and surface properties
  • 11.4 Friction
  • 11.5 Surface contact mechanics
  • 11.6 Lubrication
  • 11.7 Wear
  • 11.8 Surface contact in biomaterials
  • 11.9 Friction and wear test methods
  • 11.10 Design factors
  • 11.11 Case study: the use of composites in total joint replacements
  • 11.12 Summary
  • 11.13 Problems for consideration
  • 11.14 References
  • Part III Case studies
  • 12 Regulatory affairs and testing
  • 12.1 Historical perspective and overview
  • 12.2 Learning objectives
  • 12.3 FDA legislative history
  • 12.4 Medical device definitions and classifications
  • 12.5 CDRH organization
  • 12.6 Anatomy of a testing standard
  • 12.7 Development of testing standards
  • 12.8 International regulatory bodies
  • 12.9 Case study: examining a 510(k) approval
  • 12.10 Summary
  • 12.11 Problems for consideration
  • 12.12 References
  • 13 Orthopedics
  • 13.1 Historical perspective and overview
  • 13.2 Learning objectives
  • 13.3 Total joint replacements
  • 13.4 Total hip arthroplasty
  • 13.5 Total knee arthroplasty
  • 13.6 Fracture fixation
  • 13.7 Spinal implants
  • 13.8 Engineering challenges and design constraints of orthopedic implants
  • 13.9 Case studies
  • 13.10 Summary
  • 13.11 Looking forward in orthopedic implants
  • 13.12 Problems for consideration
  • 13.13 References
  • 14 Cardiovascular devices
  • 14.1 Historical perspective and overview
  • 14.2 Learning objectives
  • 14.3 Cardiovascular anatomy
  • 14.4 Load-bearing devices
  • 14.5 Case studies
  • 14.6 Looking forward
  • 14.7 Summary
  • 14.8 Problems for consideration
  • 14.9 References
  • 15 Oral and maxillofacial devices
  • 15.1 Overview
  • 15.2 Learning objectives
  • 15.3 Oral and maxillofacial anatomy
  • 15.4 Dental implants
  • 15.5 Temporomandibular joint replacements
  • 15.6 Case studies
  • 15.7 Looking forward
  • 15.8 Summary
  • 15.9 Problems for consideration
  • 15.10 References
  • 16 Soft tissue replacements
  • 16.1 Historical perspective and overview
  • 16.2 Learning objectives
  • 16.3 Sutures
  • 16.4 Synthetic ligament
  • 16.5 Artificial skin
  • 16.6 Ophthalmic implants
  • 16.7 Cosmetic implants
  • 16.8 Case studies
  • 16.9 Looking forward
  • 16.10 Summary
  • 16.11 Problems for consideration
  • 16.12 References
  • Epilogue
  • Appendix A. Selected topics from mechanics of materials
  • Appendix B. Table of material properties of engineering biomaterials and tissues
  • Appendix C. Teaching methodologies in biomaterials
  • Glossary
  • Index