ISE Human Genetics
Höfundur:
Ricki Lewis (Útgáfa: 14)
Kaup valmöguleikar
Human Genetics: Concepts and Applications embraces the broadening of human genetics from an academic and medical discipline to an informational science that can be highly personal, yet have societal impact. By coming to know genetic backgrounds, people can control their environments in more healthy ways. Genetic knowledge is, therefore, both informative and empowering.
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- McGraw-Hill Higher Education (International)
- 9781266450006
- 9781266283192
- ePub
- 14
- Ricki Lewis
- English
- 2023-09-05
- 100
- 2
- 2
Kaflar
- Cover
- Title Page
- Copyright Page
- Contents
- About the Author
- Preface
- Applying Human Genetics
- The Human Touch
- The Lewis Guided Learning System
- part 1 Introduction
- chapter 1: The Information in a Human Genome
- 1.1 Introducing Genes and Genomes
- 1.2 Levels of Genetics and Genomics
- 1.3 Applications of Genetics and Genomics
- 1.4 A Global Perspective on Genomes
- chapter 2: Cells
- 2.1 Introducing Cells
- 2.2 Cell Components
- 2.3 Cell Division and Death
- 2.4 Stem Cells
- 2.5 The Human Microbiome
- chapter 3: Meiosis, Development, and Aging
- 3.1 The Reproductive System
- 3.2 Meiosis
- 3.3 Gametes Mature
- 3.4 Prenatal Development
- 3.5 Congenital Disorders
- 3.6 Maturation and Aging
- part 2 Transmission Genetics
- chapter 4: Single-Gene Inheritance
- 4.1 Following the Inheritance of One Gene
- 4.2 Single-Gene Inheritance Is Rare
- 4.3 Following the Inheritance of More Than One Gene
- 4.4 Pedigree Analysis
- chapter 5: Beyond Mendel’s Laws
- 5.1 When Gene Expression Appears to Alter Mendelian Ratios
- 5.2 Mitochondrial Genes
- 5.3 Linkage
- chapter 6: Matters of Sex
- 6.1 Our Sexual Selves
- 6.2 Traits Inherited on Sex Chromosomes
- 6.3 Sex-Limited and Sex-Influenced Traits
- 6.4 X Inactivation
- 6.5 Parent-of-Origin Effects
- chapter 7: Complex Traits
- 7.1 Genes and the Environment Mold Traits
- 7.2 Polygenic Traits Are Continuously Varying
- 7.3 Methods to Investigate Complex Traits
- 7.4 A Closer Look: Body Weight
- chapter 8: Genetics of Behavior
- 8.1 Genes and Behavior
- 8.2 Sleep
- 8.3 Intelligence and Intellectual Disability
- 8.4 Drug Addiction
- 8.5 Mood Disorders
- 8.6 Schizophrenia
- 8.7 Autism
- part 3 DNA and Chromosomes
- chapter 9: DNA Structure and Replication
- 9.1 Experiments Identify and Describe the Genetic Material
- 9.2 DNA Structure
- 9.3 DNA Replication—Maintaining Genetic Information
- 9.4 Sequencing DNA
- chapter 10: Gene Action: From DNA to RNA to Protein
- 10.1 The Importance of Proteins
- 10.2 Transcription Copies the Information in DNA into RNA
- 10.3 Translation of a Protein
- 10.4 Processing a Protein
- chapter 11: Gene Expression and Epigenetics
- 11.1 Gene Expression Through Time and Tissue
- 11.2 Control of Gene Expression
- 11.3 Maximizing Genetic Information
- chapter 12: Gene Mutation
- 12.1 The Nature of Gene Variants
- 12.2 Allelic Diseases
- 12.3 Causes of Mutation
- 12.4 Types of Mutations
- 12.5 The Importance of Position
- 12.6 DNA Repair
- chapter 13: Chromosomes
- 13.1 Portrait of a Chromosome
- 13.2 Detecting Chromosomes
- 13.3 Atypical Chromosome Number
- 13.4 Atypical Chromosome Structure
- 13.5 Uniparental Disomy—A Double Dose from One Parent
- chapter 14: Genomes
- 14.1 From Genetics to Genomics
- 14.2 The Human Pangenome
- 14.3 Human Genome Content
- 14.4 Genomic Medicine
- part 4 Population Genetics
- chapter 15: Constant Allele Frequencies
- 15.1 Population Genetics Underlies Evolution
- 15.2 Constant Allele Frequencies
- 15.3 Applying Hardy-Weinberg Equilibrium
- chapter 16: Changing Allele Frequencies
- 16.1 Population Matters: Steel Syndrome in East Harlem
- 16.2 Nonrandom Mating
- 16.3 Migration
- 16.4 Genetic Drift
- 16.5 Mutation
- 16.6 Natural Selection
- 16.7 Eugenics
- chapter 17: Human Ancestry and Evolution
- 17.1 Human Origins
- 17.2 Methods to Study Molecular Evolution
- 17.3 The Peopling of the Planet
- 17.4 What Makes Us Human?
- chapter 18: The Genetics of Identity
- 18.1 Genetics as an Informational Science
- 18.2 Forensic DNA Typing
- 18.3 Genetic Genealogy
- 18.4 Forensic STRs Meet Genetic Genealogy SNPs
- part 5 Immunity and Cancer
- chapter 19: Genetics of Immunity
- 19.1 The Importance of Cell Surfaces
- 19.2 The Human Immune System
- 19.3 Atypical Immunity
- 19.4 The Immune Response During Pregnancy
- 19.5 Altering Immunity
- chapter 20: Cancer Genetics and Genomics
- 20.1 Cancer Is an Abnormal Growth That Invades and Spreads
- 20.2 Cancer at the Cellular Level
- 20.3 Cancer Genes and Genomes
- 20.4 Diagnosing and Treating Cancer
- part 6 Genetic Technology
- chapter 21: DNA and RNA Technologies
- 21.1 Patenting DNA and RNA
- 21.2 Modifying DNA
- 21.3 Monitoring Gene Function
- 21.4 Gene Silencing and Genome Editing
- chapter 22: Genetic Testing and Treatment
- 22.1 Genetic Counseling
- 22.2 Genetic Screening and Testing
- 22.3 Treating Genetic Disease
- 22.4 CRISPR-Cas9 in Health Care
- chapter 23: Reproductive Technologies
- 23.1 Savior Siblings and More
- 23.2 Infertility and Subfertility
- 23.3 Assisted Reproductive Technologies
- 23.4 Extra Embryos
- Answers to Key Concepts Questions A-1
- Index I-1