Clinical Pharmacology and Practical Prescribing on the Move
Höfundar:
James Turnbull; Matthew Tate (Útgáfa: 1)
Kaup valmöguleikar
The Medicine on the Move series provides fully-flexible access to subjects across the curriculum, in this case clinical pharmacology and prescribing practice, in a combination of print and mobile formats. The books are ideal for the busy medical student and junior doctor, irrespective of individual learning style and whether they are studying a subject for the first time or revisiting it during exam preparation, providing the right information whenever and wherever it is needed.
Nánar um bókina
- Taylor & Francis
- 9781040177037
- 9781444176032
- ePub
- 1
- James Turnbull; Matthew Tate
- English
- 2016-03-30
- 100
- 2
- 2
Kaflar
- Cover
- Half Title
- Title Page
- Copyright Page
- Table of Contents
- Preface
- Authors
- Editorial Advisor
- Editor-In-Chief
- Series Editors
- Acknowledgements
- List of abbreviations
- Drug Dosing and Routes of Administration
- Abbreviations
- An explanation of the text
- Part I Clinical pharmacology
- 1 Clinical pharmacokinetics
- 1.1 Basic Principles of Pharmacokinetics
- Drug Concentration/Time Curve
- Bioavailability
- HALF-LIFE (t½)
- Stedy State (SS)
- The Apparent 'volume Of Distribution' (Vd)
- Compartment models
- Linear and Non-Linear Pharmacokinetics
- Linear (first order) kinetics
- Non-linear (zero order) kinetics
- Zero order kinetics
- 2 Clinical application of pharmacokinetics
- 2.1 Principles of Dosing
- 2.2 Loading Doses
- Principles of Loading Doses
- 2.3 Maintenance Dosing
- 2.4 Therapeutic Drug Monitoring
- Drug Properties
- Timing of Doses and Plasma Levels
- 3 Pharmacodynamics
- 3.1 Basic Principles of Drug Action
- Non-Specific Mechanisms
- Specific Mechanisms
- Drug-protein binding
- Specificity of binding
- Drug-protein interactions
- Mechanisms of clinical effects
- Agonists
- Variable effects of agonists
- Antagonists
- Irreversible and competitive antagonism
- Slow processes
- Clinical response of drug-protein interactions
- Receptor mechanisms
- Ligand gated ion channels
- G-protein coupled receptors
- Enzyme linked receptors
- Intranuclear receptors
- Site-specific non-receptor mechanisms
- Enzyme interactions
- Transporters
- Ion channels (voltage gated)
- Active transport systems
- 4 Drug handling by the body
- 4.1 Drug Route and Absorption
- Oral Route
- Parenteral Routes
- Intravenous
- Intramuscular and subcutaneous
- Buccal, Sublingual and Rectal
- Topical
- 4.2 Metabolism
- Drug Factors
- Metabolism as a function
- Route Factors
- Physiological Factors
- Hepatic metabolism
- Phase I metabolism
- Phase II Metabolism
- Enzyme induction and inhibition
- 4.3 Excretion
- Renal Excretion
- Biliary Excretion
- Part II Drugs and practical prescribing
- 5 Cardiovascular drugs
- 5.1 Positive Inotropes
- Cardiac Glycosides (Digoxin)
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- 5.2 Diuretics
- Thiazide Diuretics
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Loop Diuretics
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Potassium-Sparing Diuretics
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Examples
- Aldosterone antagonists
- Potassium sparing diuretics
- Special requirements
- Other Diuretics
- 5.3 Antiarrhythmic Drugs
- Classification of Drugs for Arrhythmias
- Treatment Algorithm for Arrhythmias
- Supraventricular (narrow complex) arrhythmias
- Regular rhythm
- Irregular rhythm
- Ventricular (broad complex) arrhythmias
- Regular rhythm
- Irregular rhythm
- Classes of Antiarrhythmic Drugs
- Class I antiarrhythmics
- Adenosine
- Amiodarone and related drugs
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Examples
- Special requirements
- 5.4 Adrenoceptor Antagonists
- α-Adrenoceptor Blocking Drugs
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Examples and dosing
- β-Adrenoceptor Blocking Drugs
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Examples
- Non-selective
- 5.5 Antihypertensive and Related Medications
- Initiating Antihypertensive Medication
- Centrally Acting Antihypertensives
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Special requirements
- Vasodilator Antihypertensives
- Drugs Affecting the Renin-Angiotensin System
- Pharmacodynamics
- Renin-Angiotensin-Aldosterone system
- ACE inhibitors
- ARBs
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Examples
- ACE inhibitors
- ARBs
- Special requirements
- 5.6 Antianginal and Related Drugs
- Nitrates
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- CALCIUM CHANNEL BLOCKERS (CCBs)
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Dihydropyridines
- Non-dihydropyridines
- Important interactions
- Examples and dosing
- Dihydropyridines
- Non-dihydropyridines
- Other Antianginals
- Nicorandil (Ikorel®)
- Ivabradine (Procoralan®)
- Ranolazine (Ranexa®)
- 5.7 Antiplatelet Drugs
- Aspirin
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- ADP Antagonists
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Examples and dosing
- Dipyridamole
- Glycoprotein IIB/IIIA Inhibitors
- 5.8 Lipid-Lowering Drugs
- Stains
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples and dosing
- Special requirements
- Fibrates
- Ezetimibe
- Bile Acid Sequestrants
- Nicotinic Acid and Related Drugs
- Omega-3 Fatty Acids
- 5.9 Fibrinolytic Drugs
- Pharmacodynamics
- Indications
- Cautions/contraindications
- Examples and dosing
- 5.10 Antifibrinolytic Drugs
- 6 Respiratory drugs
- 6.1 Inhaled Therapy
- Inhaler devices
- Nebulized therapy
- 6.2 Bronchodilators
- Beta2 Agonists
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Muscarinic Antagonists
- Pharmacodynamics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Theophylline
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Leukotriene Receptor Antagonists
- Pharmacodynamics
- Indications
- Adverse effects
- Examples
- 6.3 Inhaled Corticosterioids
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- 6.4 Other Respiratory Medications
- Antihistamines (H1 Receptor Antagonists)
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Sedating
- Non-sedating
- Special requirements
- Mucolytics
- Pharmacodynamics
- Indications
- Cautions
- Adverse effects
- Examples
- 7 Gastrointestinal drugs
- 7.1 Acid Suppressant Drugs
- H2 Receptor Antagonists
- Pharmacodynamics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- PROTON PUMP INHIBITORS (PPIs)
- Pharmacodynamics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- 7.2 Drugs Used in Inflammatory Bowel Disease (IBD)
- Step-Wise Management of IBD
- Aminosalicylates
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Corticosteroid Preparations
- 7.3 Other Gastrointestinal Medications
- Loperamide
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Adverse effects
- Laxatives
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Examples
- Special requirements
- Mebeverine and Alverine
- Pharmacodynamics
- Indications
- Contraindications
- Adverse effects
- Examples
- Antimuscarinic Antispasmodics
- Pharmacodynamics
- Indications
- Contraindications
- Cautions, adverse effects, interactions
- Examples
- 7.4 Anti-Emetic Drugs
- Pathophysiology of Nausea and Vomiting
- 5-HT3 Antagonists
- Pharmacodynamics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Dopamine Antagonists as Anti-Emetics
- Pharmacodynamics
- Indications
- Cautions and contraindications, adverse effects, interactions and examples
- Antihistamine Anti-Emetics
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Metoclopramide and Domperidone
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Examples
- 7.5 Anti-Obesity Drugs
- Orlistat
- 8 Neurological medications
- 8.1 Parkinson's Disease and Other Movement Disorders
- General Principles
- Levodopa (And Dopa-Decarboxylase Inhibitors)
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Dopamine Receptor Agonists
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Comt Inhibitors (Catechol-O-Methyl Transferase)
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- MAOB Inhibitors (Monoamine Oxidase)
- Pharmacodynamics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Antimuscarinic Drugs
- Pharmacodynamics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Amantadine
- 8.2 Antidepressant Medication
- General Principles
- SSRIs (Selective Serotonin Reuptake Inhibitors)
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Tricyclic Antidepressants (TCAs)
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Related Non-Tricyclic Antidepressants
- Monoamine-Oxidase Inhibitors (MAOIs)
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Other Antidepressants
- Serotonin-noradrenaline reuptake inhibitors (SNRIs)
- Noradrenaline reuptake inhibitors (NRIs)
- 8.3 Antiepileptic Medications
- General Principles
- Mechanism of action of antiepileptic medications
- Choice
- Pregnancy
- Withdrawal
- Interactions
- Driving
- Carbamazepine and Related Antiepileptic Drugs
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Sodium Valproate
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples and dosing
- Special requirements
- Phenytoin
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Topiramate Topamax®
- Gabapentin and Pregabalin
- Pharmacodynamics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Lamotrigine
- Pharmacodynamics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Barbiturates and Related Drugs
- Benzodiazepines
- Pharmacodynamics, cautions, adverse effects
- Examples and dosing
- Status Epilepticus
- First line treatment
- Second line treatment
- Refractory epilepsy
- Other agents
- 8.4 Antipsychotic (Neuroleptic) Medications
- General Principles
- Pathophysiology of schizophrenia and antipsychotic medications
- Classification of antipsychotics
- First generation (typical) antipsychotics
- Second generation (atypical) antipsychotics
- Adverse effects
- Choice
- First Generation 'Typical' Antipsychotics
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Phenothiazine derivatives
- Butyrophenones
- Thioxanthenes
- Substituted benzamides
- Second Generation 'Atypical' Antipsychotics
- Pharmacodynamics
- Indications
- Contraindications and cautions
- Important interactions
- Adverse effects
- Examples
- 8.5 Hypnotic and Anxiolytic Medications
- General Principles
- Benzodiazepines
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Anxiolytics
- Hypnotics
- Other benzodiazepines
- Non-Benzodiazepine Hypnotics (Z-Drugs)
- 8.6 Medications for Bipolar Disorder and Mania
- General Principles
- Bipolar affective disorder
- Acute mania control
- Prophylaxis of mania and bipolar disorder
- Lithium
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- 8.7 CNS Stimulants
- General Principles
- Examples and dosing
- 8.8 Drug Use in Dementia
- General Principles
- Acetylcholinesterase inhibitors
- NMDA receptor antagonist
- Antipsychotics
- 8.9 Drug Use in Substance Dependence
- Alcohol dependence
- Smoking cessation
- Opioid dependence
- 9 Endocrinology
- 9.1 Treatment of Diabetes
- General Principles
- Insulin
- Anti-Diabetic Medications
- Biguanides (metformin)
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Examples
- Special requirements
- Sulphonylureas
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Examples
- Other Anti-Diabetic Medications
- Acarbose
- Thiazolidinediones (glitazones)
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Examples
- Special requirements
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Examples
- Dipeptidylpeptidase (DPP-4) inhibitors (gliptins)
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Examples, specific cautions and special requirements
- GLP-1 (glucagon like peptide-1) receptor agonists
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Examples, specific cautions and special requirements
- Special requirements
- 9.2 Treatment of Thyroid Disorders
- Thyroid Hormones
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Examples
- Special requirements
- Thionamides (Anti-Thyroid Therapy)
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Examples
- 9.3 Corticosteroid Therapy
- General Principles
- Glucocorticoids
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Examples
- Special requirement
- Mineralocorticoids
- Indications
- 10 Analgesia
- 10.1 Principles of Prescribing Analgesia
- Causes of Pain
- Strategies for Pain Suppression
- Nociception
- Block primary afferent
- Interact with high level perception
- Time Line of Pain
- Chronic pain
- Rational prescribing of analgesia
- Acute pain
- Post-operative pain
- 10.2 Simple Analgesia
- Drug Profiles
- Paracetamol
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Dosing
- Special requirements
- Nefopam
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Dosing
- Special requirements
- 10.3 NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs)
- Drug Profiles
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Examples and dosing
- Choice of Nsaid
- 10.4 Opiates
- Drug Profiles
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples and dosing
- Weak opioids
- Strong opioids
- Special requirements
- Opiate Dose Conversion Guide
- 11 Antimicrobials I: Antibacterials
- 11.1 Principles of Antibiotic Therapy
- Starting Antibiotic Therapy
- Sensitivity and Resistance
- Sensitivity testing and antibacterial activity
- Antibiotic resistance
- Pharmacokinetic Considerations
- Absorption
- Distribution
- Metabolism
- Elimination
- 11.2 Antibiotic Classes
- Beta-Lactams
- Penicillins
- Examples
- Beta-lactamase inhibitors and extended spectrum penicillins
- Beta-lactamase inhibitors (and flucloxacillin)
- Extended spectrum penicillins
- Examples
- Cephalosporins
- First generation
- Second generation
- Third generation
- Advanced generations
- Carbapenems
- Examples
- Monobactams (mono-cyclic beta-lactam)
- Glycopeptides
- Main adverse effects
- Examples
- Macrolides
- Adverse effects
- Examples
- Tetracyclines
- Examples
- Aminoglycosides
- Adverse effects
- Examples
- Quinolones
- Adverse effects
- Examples
- Other Antibiotics
- Metronidazole
- Clindamycin
- Chloramphenicol
- Trimethoprim/co-trimoxazole
- Nitrofurantoin
- Daptomycin (Cubicin®)
- Fusidic acid
- Linezolid (Zyvox®)
- Anti-Tuberculous Agents
- 12 Antimicrobials II: Antivirals and antifungals
- 12.1 Antiretrovirals
- NUCLEOSIDE REVERSE TRANSCRIPTASE INHABITORS (NRTIs)
- Pharmacodynamics
- Adverse effects
- Examples
- NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS (NNRTIs)
- Pharmacodynamics
- Adverse effects
- Examples
- Protease Inhibitors
- Pharmacodynamics
- Adverse effects
- Examples
- Other Agents
- Integrase inhibitors
- Fusion inhibitors
- CCR5 receptor antagonists
- Antiretroviral drug combinations
- 12.2 Other Antiviral Agents
- Aciclovir and Related Drugs
- Ganciclovir and Drugs Active Against Cytomegalovirus (CMV)
- Oseltamivir and Zanamivir
- Drugs Used in Viral Hepatitis
- Hepatitis C
- Hepatitis B
- 12.3 Antifungal Drugs
- Triazoles
- Imidazoles
- Polyenes
- Other Agents
- 13 Musculoskeletal and metabolic drugs
- 13.1 Calcium and Bone Metabolism
- General Principles
- Bisphosphonates
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Calcitonin and Parathyroid Hormones
- Calcitonin
- Parathyroid hormone and related drugs
- Strontium Ranelate
- 13.2 Neuromuscular Drugs
- Skeletal Muscle Relaxants
- Baclofen
- Dantrolene
- Tizanidine
- Anticholinesterases (Acetyl Cholinesterase Inhibitors)
- Pharmacodynamics
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Quinine
- Adverse effects
- Dosing
- 13.3 Gout
- Treatment of Acute Gout
- General principles
- Colchicine
- Pharmacodynamics
- Indications
- Cautions
- Contraindications
- Adverse effects
- Important interactions
- Control of Chronic Gout
- General principles
- Allopurinol
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Contraindications
- Adverse effects
- Important interactions
- 14 Prescribing anticoagulants
- 14.1 Anticoagulation
- Blood Coagulation Cascade
- Warfarin
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Adverse effects
- Important interactions
- Monitoring
- Initiation of treatment
- Rapid anticoagulation
- Slow anticoagulation
- Bridging protocols
- Overdose/overtreatment
- Avoiding prescribing errors
- The Heparins
- General principles and pharmacodynamics
- Low molecular weight heparins
- Pharmacokinetics
- Indications
- Examples
- Unfractionated heparin (UFH)
- Pharmacokinetics
- Indications
- Initiation of treatment and dosing
- Monitoring
- Adverse effects (both UFH and LMWH)
- Fondaparinux
- DIRECT FACTOR Xa INHIBITORS
- Other Anticoagulants
- Direct thrombin inhibitors
- Heparinoids
- 15 Prescribing of fluids
- 15.1 Intravenous Fluids, Infusions and Electrolytes
- Fluid Compartments and Daily Requirements
- Fluid compartments
- Daily fluid and electrolyte requirements
- Formulated Intravenous Fluids
- Crystalloids
- Hypotonic (and relatively hypotonic)
- Isotonic
- Hypertonic
- Colloids
- Fluid Prescribing
- Maintenance fluids
- Fluid replacement
- Resuscitation
- Electrolyte Disturbances
- Potassium
- Hyperkalaemia
- Causes
- Clinical features
- Management
- Hypokalaemia
- Causes
- Clinical features
- Management
- Sodium
- Hypernatraemia (Na+ >150 mmol/L)
- Causes
- Clinical features
- Management
- Hyponatraemia (Na+ <130 mmol/L)
- Causes
- Clinical features
- Management
- Calcium
- Hypercalcaemia (Ca2+ >2.65 mmol/L)
- Causes
- Clinical features
- Management
- Hypocalcaemia (Ca2+ <2.2 mmol/L)
- Causes
- Clinical features
- Management
- Magnesium
- Hypomagnesaemia (Mg2+ <0.7 mmol/L)
- Causes
- Clinical features
- Management
- Phosphate
- Hypophosphataemia (PO43- <0.8 mmol/L)
- Causes
- Clinical features
- Management
- 16 Prescribing in diabetes
- 16.1 Insulin and Prescribing in Diabetes
- Pharmacodynamics
- Types of Insulin
- Quick acting
- Short-acting soluble insulin
- Rapid acting insulin analogues
- Intermediate/long acting
- Isophane insulin
- Long acting insulin analogues (lente insulin)
- Mixed insulins
- Insulin Regimes
- Type 1 diabetes
- Type 2 diabetes
- Insulin and Dose Changes
- High blood sugars
- Low blood sugars
- Avoiding Prescribing Errors
- Insulin Infusions and Sliding Scales
- Fixed rate insulin (diabetic emergencies)
- Diabetic ketoacidosis (DKA)
- Hyperosmolar hyperglycaemic state (HHS)
- Sliding scale regimens
- General principles
- Prescribing
- Hypoglycaemia
- Restarting patients usual insulin/oral hypoglycaemic regimen
- Pre-Operative Patients
- 17 Immunosuppressants
- 17.1 Immunosuppressant and Immunomodulatory Drugs
- Azathioprine and 6-Mercaptopurine (6-MP)
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Contraindications
- Adverse effects
- Important interactions
- Special requirements
- Methotrexate
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Contraindications
- Adverse effects
- Important interactions
- Special requirements
- Sulfasalazine
- Leflunomide Arava®
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Contraindications
- Adverse effects
- Important interactions
- Special requirements
- Ciclosporin
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Contraindications
- Adverse effects
- Important interactions
- Special requirements
- Anti-TNF-α Agents
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Contraindications
- Adverse effects
- Examples
- Special requirements
- 18 Inotropes
- 18.1 Inotropic Drugs (Reference Only)
- Background
- Part III Self-assessment
- 19 Adverse drug reactions
- Case Presentation 1
- Question 1
- Adverse Effect Options
- Case Presentation 2
- Question 2
- Adverse Effect Options
- Case Presentation 3
- Question 3
- Adverse Effect Options
- Case Presentation 4
- Question 4
- Adverse Effect Options
- Case Presentation 5
- Question 5
- Adverse Effect Options
- Case Presentation 6
- Question 6
- Adverse Effect Options
- Case Presentation 7
- Question 7
- Adverse Effect Options
- Case Presentation 8
- Question 8
- Adverse Effect Options
- Answers
- Answer 1: C
- Answer 2: D
- Answer 3: E
- Answer 4: C
- Answer 5: C
- Answer 6: D
- Answer 7: B
- Answer 8: D
- 20 Communicating information
- Case Presentation 1
- Question 1
- Information Options
- Case Presentation 2
- Question 2
- Information Options
- Case Presentation 3
- Question 3
- Information Options
- Case Presentation 4
- Question 4
- Information Options
- Case Presentation 5
- Question 5
- Information Options
- Case Presentation 6
- Question 6
- Information Options
- Answers
- Answer 1: C
- Answer 2: E
- Answer 3: D
- Answer 4: C
- Answer 5: D
- Answer 6: E
- 21 Calculation skills
- Case Presentation 1
- Calculation 1
- Case Presentation 2
- Calculation 2
- Case Presentation 3
- Calculation 3
- Case Presentation 4
- Calculation 4
- Case Presentation 5
- Calculation 5
- Case Presentation 6
- Calculation 6
- Case Presentation 7
- Calculation 7
- Case Presentation 8
- Calculation 8
- Answers
- Workings
- Workings
- Workings
- Workings
- Workings
- Workings
- Workings
- Workings
- 22 Drug monitoring
- Case Presentation 1
- Question 1
- Monitoring Options
- Case Presentation 2
- Question 2
- Monitoring Options
- Case Presentation 3
- Question 3
- Monitoring Options
- Case Presentation 4
- Question 4
- Monitoring Options
- Case Presentation 5
- Question 5
- Monitoring Options
- Case Presentation 6
- Question 6
- Monitoring Options
- Case Presentation 7
- Question 7
- Monitoring Options
- Case Presentation 8
- Question 8
- Monitoring Options
- Answers
- Answer 1: B
- Answer 2: B
- Answer 3: B
- Answer 4: C
- Answer 5: C
- Answer 6: D
- Answer 7: E
- Answer 8: A
- 23 Data interpretation
- Case Presentation 1
- Question 1
- Decision Options
- Case Presentation 2
- Question 2
- Decision Options
- Case Presentation 3
- Question 3
- Decision Options
- Case Presentation 4
- Question 4
- Decision Options
- Case Presentation 5
- Question 5
- Decision Options
- Case Presentation 6
- Question 6
- Decision Options
- Answers
- Answer 1: D
- Answer 2: A
- Answer 3: E
- Answer 4: D
- Answer 5: E
- Answer 6: C
- 24 Planning management
- Case Presentation 1
- Question 1
- Management Options
- Case Presentation 2
- Question 2
- Management Options
- Case Presentation 3
- Question 3
- Management Options
- Case Presentation 4
- Question 4
- Management Options
- Answers
- Answer 1: D
- Answer 2: C
- Answer 3: A
- Answer 4: B
- 25 Prescription review
- Case Presentation 1
- Current Prescriptions
- Question 1A
- Question 1B
- Case Presentaion 2
- Current Prescriptions
- Question 2A
- Question 2B
- Case Presentation 3
- Current Prescriptions
- Question 3A
- Question 3B
- Case Presentation 4
- Current Prescriptions
- Question 4A
- Question 4B
- Question 4C
- Case Presentation 5
- Current Prescriptions
- Question 5A
- Case Presentation 6
- Current Prescriptions
- Question 6A
- Question 6B
- Case Presentation 7
- Current Medications
- Question 7A
- Question 7B
- Case Presentation 8
- Current Medications
- Question 8A
- Question 8B
- Answers
- Answer 1A: C
- Answer 1B: D, E, H
- Answer 2A: B, E
- Answer 2B: A, D
- Answer 3A: F, G
- Answer 3B: C
- Answer 4A: J
- Answer 4B: E, H
- Answer 4C: G
- Answer 5A: C, D, F, G, H
- Answer 6A: B, E
- Answer 6B: A, F
- Answer 7A: F, G
- Answer 7B: B, E
- Answer 8A: A, C
- Answer 8B: F, G
- 26 Prescribing
- Questions
- Background
- Question Information
- Scenario 1
- Scenario 2
- Scenario 3
- Scenario 4
- Scenario 5
- Scenario 6
- Scenario 7
- Scenario 8
- Answers
- Scenario 1
- Scenario 2
- Scenario 3
- Scenario 4
- Scenario 5
- Scenario 6
- Scenario 7
- Scenario 8
- Index