Clinical Pharmacology and Practical Prescribing on the Move
Höfundar:
James Turnbull; Matthew Tate (Útgáfa: 1)
Kaup valmöguleikar
The Medicine on the Move series provides fully-flexible access to subjects across the curriculum, in this case clinical pharmacology and prescribing practice, in a combination of print and mobile formats. The books are ideal for the busy medical student and junior doctor, irrespective of individual learning style and whether they are studying a subject for the first time or revisiting it during exam preparation, providing the right information whenever and wherever it is needed.
Readers can choose from the book and the eBook to suit different situations, enabling them to benefit from learning medicine on the move. Print Versions of this book also include access to the ebook version.
Nánar um bókina
- Taylor & Francis
- 9781040177037
- 9781444176032
- ePub
- 1
- James Turnbull; Matthew Tate
- English
- 2016-03-30
- 100
- 2
- 2
Kaflar
- Cover
- Half Title
- Title Page
- Copyright Page
- Table of Contents
- Preface
- Authors
- Editorial Advisor
- Editor-In-Chief
- Series Editors
- Acknowledgements
- List of abbreviations
- Drug Dosing and Routes of Administration
- Abbreviations
- An explanation of the text
- Part I Clinical pharmacology
- 1 Clinical pharmacokinetics
- 1.1 Basic Principles of Pharmacokinetics
- Drug Concentration/Time Curve
- Bioavailability
- HALF-LIFE (t½)
- Stedy State (SS)
- The Apparent 'volume Of Distribution' (Vd)
- Compartment models
- Linear and Non-Linear Pharmacokinetics
- Linear (first order) kinetics
- Non-linear (zero order) kinetics
- Zero order kinetics
- 2 Clinical application of pharmacokinetics
- 2.1 Principles of Dosing
- 2.2 Loading Doses
- Principles of Loading Doses
- 2.3 Maintenance Dosing
- 2.4 Therapeutic Drug Monitoring
- Drug Properties
- Timing of Doses and Plasma Levels
- 3 Pharmacodynamics
- 3.1 Basic Principles of Drug Action
- Non-Specific Mechanisms
- Specific Mechanisms
- Drug-protein binding
- Specificity of binding
- Drug-protein interactions
- Mechanisms of clinical effects
- Agonists
- Variable effects of agonists
- Antagonists
- Irreversible and competitive antagonism
- Slow processes
- Clinical response of drug-protein interactions
- Receptor mechanisms
- Ligand gated ion channels
- G-protein coupled receptors
- Enzyme linked receptors
- Intranuclear receptors
- Site-specific non-receptor mechanisms
- Enzyme interactions
- Transporters
- Ion channels (voltage gated)
- Active transport systems
- 4 Drug handling by the body
- 4.1 Drug Route and Absorption
- Oral Route
- Parenteral Routes
- Intravenous
- Intramuscular and subcutaneous
- Buccal, Sublingual and Rectal
- Topical
- 4.2 Metabolism
- Drug Factors
- Metabolism as a function
- Route Factors
- Physiological Factors
- Hepatic metabolism
- Phase I metabolism
- Phase II Metabolism
- Enzyme induction and inhibition
- 4.3 Excretion
- Renal Excretion
- Biliary Excretion
- Part II Drugs and practical prescribing
- 5 Cardiovascular drugs
- 5.1 Positive Inotropes
- Cardiac Glycosides (Digoxin)
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- 5.2 Diuretics
- Thiazide Diuretics
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Loop Diuretics
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Potassium-Sparing Diuretics
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Examples
- Aldosterone antagonists
- Potassium sparing diuretics
- Special requirements
- Other Diuretics
- 5.3 Antiarrhythmic Drugs
- Classification of Drugs for Arrhythmias
- Treatment Algorithm for Arrhythmias
- Supraventricular (narrow complex) arrhythmias
- Regular rhythm
- Irregular rhythm
- Ventricular (broad complex) arrhythmias
- Regular rhythm
- Irregular rhythm
- Classes of Antiarrhythmic Drugs
- Class I antiarrhythmics
- Adenosine
- Amiodarone and related drugs
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Examples
- Special requirements
- 5.4 Adrenoceptor Antagonists
- α-Adrenoceptor Blocking Drugs
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Examples and dosing
- β-Adrenoceptor Blocking Drugs
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Examples
- Non-selective
- 5.5 Antihypertensive and Related Medications
- Initiating Antihypertensive Medication
- Centrally Acting Antihypertensives
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Special requirements
- Vasodilator Antihypertensives
- Drugs Affecting the Renin-Angiotensin System
- Pharmacodynamics
- Renin-Angiotensin-Aldosterone system
- ACE inhibitors
- ARBs
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Examples
- ACE inhibitors
- ARBs
- Special requirements
- 5.6 Antianginal and Related Drugs
- Nitrates
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- CALCIUM CHANNEL BLOCKERS (CCBs)
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Dihydropyridines
- Non-dihydropyridines
- Important interactions
- Examples and dosing
- Dihydropyridines
- Non-dihydropyridines
- Other Antianginals
- Nicorandil (Ikorel®)
- Ivabradine (Procoralan®)
- Ranolazine (Ranexa®)
- 5.7 Antiplatelet Drugs
- Aspirin
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- ADP Antagonists
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Examples and dosing
- Dipyridamole
- Glycoprotein IIB/IIIA Inhibitors
- 5.8 Lipid-Lowering Drugs
- Stains
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples and dosing
- Special requirements
- Fibrates
- Ezetimibe
- Bile Acid Sequestrants
- Nicotinic Acid and Related Drugs
- Omega-3 Fatty Acids
- 5.9 Fibrinolytic Drugs
- Pharmacodynamics
- Indications
- Cautions/contraindications
- Examples and dosing
- 5.10 Antifibrinolytic Drugs
- 6 Respiratory drugs
- 6.1 Inhaled Therapy
- Inhaler devices
- Nebulized therapy
- 6.2 Bronchodilators
- Beta2 Agonists
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Muscarinic Antagonists
- Pharmacodynamics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Theophylline
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Leukotriene Receptor Antagonists
- Pharmacodynamics
- Indications
- Adverse effects
- Examples
- 6.3 Inhaled Corticosterioids
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- 6.4 Other Respiratory Medications
- Antihistamines (H1 Receptor Antagonists)
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Sedating
- Non-sedating
- Special requirements
- Mucolytics
- Pharmacodynamics
- Indications
- Cautions
- Adverse effects
- Examples
- 7 Gastrointestinal drugs
- 7.1 Acid Suppressant Drugs
- H2 Receptor Antagonists
- Pharmacodynamics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- PROTON PUMP INHIBITORS (PPIs)
- Pharmacodynamics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- 7.2 Drugs Used in Inflammatory Bowel Disease (IBD)
- Step-Wise Management of IBD
- Aminosalicylates
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Corticosteroid Preparations
- 7.3 Other Gastrointestinal Medications
- Loperamide
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Adverse effects
- Laxatives
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Examples
- Special requirements
- Mebeverine and Alverine
- Pharmacodynamics
- Indications
- Contraindications
- Adverse effects
- Examples
- Antimuscarinic Antispasmodics
- Pharmacodynamics
- Indications
- Contraindications
- Cautions, adverse effects, interactions
- Examples
- 7.4 Anti-Emetic Drugs
- Pathophysiology of Nausea and Vomiting
- 5-HT3 Antagonists
- Pharmacodynamics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Dopamine Antagonists as Anti-Emetics
- Pharmacodynamics
- Indications
- Cautions and contraindications, adverse effects, interactions and examples
- Antihistamine Anti-Emetics
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Metoclopramide and Domperidone
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Examples
- 7.5 Anti-Obesity Drugs
- Orlistat
- 8 Neurological medications
- 8.1 Parkinson's Disease and Other Movement Disorders
- General Principles
- Levodopa (And Dopa-Decarboxylase Inhibitors)
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Dopamine Receptor Agonists
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Comt Inhibitors (Catechol-O-Methyl Transferase)
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- MAOB Inhibitors (Monoamine Oxidase)
- Pharmacodynamics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Antimuscarinic Drugs
- Pharmacodynamics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Amantadine
- 8.2 Antidepressant Medication
- General Principles
- SSRIs (Selective Serotonin Reuptake Inhibitors)
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Tricyclic Antidepressants (TCAs)
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Related Non-Tricyclic Antidepressants
- Monoamine-Oxidase Inhibitors (MAOIs)
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Other Antidepressants
- Serotonin-noradrenaline reuptake inhibitors (SNRIs)
- Noradrenaline reuptake inhibitors (NRIs)
- 8.3 Antiepileptic Medications
- General Principles
- Mechanism of action of antiepileptic medications
- Choice
- Pregnancy
- Withdrawal
- Interactions
- Driving
- Carbamazepine and Related Antiepileptic Drugs
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Sodium Valproate
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples and dosing
- Special requirements
- Phenytoin
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Topiramate Topamax®
- Gabapentin and Pregabalin
- Pharmacodynamics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Lamotrigine
- Pharmacodynamics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Barbiturates and Related Drugs
- Benzodiazepines
- Pharmacodynamics, cautions, adverse effects
- Examples and dosing
- Status Epilepticus
- First line treatment
- Second line treatment
- Refractory epilepsy
- Other agents
- 8.4 Antipsychotic (Neuroleptic) Medications
- General Principles
- Pathophysiology of schizophrenia and antipsychotic medications
- Classification of antipsychotics
- First generation (typical) antipsychotics
- Second generation (atypical) antipsychotics
- Adverse effects
- Choice
- First Generation 'Typical' Antipsychotics
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Phenothiazine derivatives
- Butyrophenones
- Thioxanthenes
- Substituted benzamides
- Second Generation 'Atypical' Antipsychotics
- Pharmacodynamics
- Indications
- Contraindications and cautions
- Important interactions
- Adverse effects
- Examples
- 8.5 Hypnotic and Anxiolytic Medications
- General Principles
- Benzodiazepines
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Anxiolytics
- Hypnotics
- Other benzodiazepines
- Non-Benzodiazepine Hypnotics (Z-Drugs)
- 8.6 Medications for Bipolar Disorder and Mania
- General Principles
- Bipolar affective disorder
- Acute mania control
- Prophylaxis of mania and bipolar disorder
- Lithium
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Special requirements
- 8.7 CNS Stimulants
- General Principles
- Examples and dosing
- 8.8 Drug Use in Dementia
- General Principles
- Acetylcholinesterase inhibitors
- NMDA receptor antagonist
- Antipsychotics
- 8.9 Drug Use in Substance Dependence
- Alcohol dependence
- Smoking cessation
- Opioid dependence
- 9 Endocrinology
- 9.1 Treatment of Diabetes
- General Principles
- Insulin
- Anti-Diabetic Medications
- Biguanides (metformin)
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Examples
- Special requirements
- Sulphonylureas
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Examples
- Other Anti-Diabetic Medications
- Acarbose
- Thiazolidinediones (glitazones)
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Examples
- Special requirements
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Examples
- Dipeptidylpeptidase (DPP-4) inhibitors (gliptins)
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Examples, specific cautions and special requirements
- GLP-1 (glucagon like peptide-1) receptor agonists
- Pharmacodynamics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Examples, specific cautions and special requirements
- Special requirements
- 9.2 Treatment of Thyroid Disorders
- Thyroid Hormones
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Examples
- Special requirements
- Thionamides (Anti-Thyroid Therapy)
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Examples
- 9.3 Corticosteroid Therapy
- General Principles
- Glucocorticoids
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Examples
- Special requirement
- Mineralocorticoids
- Indications
- 10 Analgesia
- 10.1 Principles of Prescribing Analgesia
- Causes of Pain
- Strategies for Pain Suppression
- Nociception
- Block primary afferent
- Interact with high level perception
- Time Line of Pain
- Chronic pain
- Rational prescribing of analgesia
- Acute pain
- Post-operative pain
- 10.2 Simple Analgesia
- Drug Profiles
- Paracetamol
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Dosing
- Special requirements
- Nefopam
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Dosing
- Special requirements
- 10.3 NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs)
- Drug Profiles
- Pharmacodynamics
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Examples and dosing
- Choice of Nsaid
- 10.4 Opiates
- Drug Profiles
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples and dosing
- Weak opioids
- Strong opioids
- Special requirements
- Opiate Dose Conversion Guide
- 11 Antimicrobials I: Antibacterials
- 11.1 Principles of Antibiotic Therapy
- Starting Antibiotic Therapy
- Sensitivity and Resistance
- Sensitivity testing and antibacterial activity
- Antibiotic resistance
- Pharmacokinetic Considerations
- Absorption
- Distribution
- Metabolism
- Elimination
- 11.2 Antibiotic Classes
- Beta-Lactams
- Penicillins
- Examples
- Beta-lactamase inhibitors and extended spectrum penicillins
- Beta-lactamase inhibitors (and flucloxacillin)
- Extended spectrum penicillins
- Examples
- Cephalosporins
- First generation
- Second generation
- Third generation
- Advanced generations
- Carbapenems
- Examples
- Monobactams (mono-cyclic beta-lactam)
- Glycopeptides
- Main adverse effects
- Examples
- Macrolides
- Adverse effects
- Examples
- Tetracyclines
- Examples
- Aminoglycosides
- Adverse effects
- Examples
- Quinolones
- Adverse effects
- Examples
- Other Antibiotics
- Metronidazole
- Clindamycin
- Chloramphenicol
- Trimethoprim/co-trimoxazole
- Nitrofurantoin
- Daptomycin (Cubicin®)
- Fusidic acid
- Linezolid (Zyvox®)
- Anti-Tuberculous Agents
- 12 Antimicrobials II: Antivirals and antifungals
- 12.1 Antiretrovirals
- NUCLEOSIDE REVERSE TRANSCRIPTASE INHABITORS (NRTIs)
- Pharmacodynamics
- Adverse effects
- Examples
- NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS (NNRTIs)
- Pharmacodynamics
- Adverse effects
- Examples
- Protease Inhibitors
- Pharmacodynamics
- Adverse effects
- Examples
- Other Agents
- Integrase inhibitors
- Fusion inhibitors
- CCR5 receptor antagonists
- Antiretroviral drug combinations
- 12.2 Other Antiviral Agents
- Aciclovir and Related Drugs
- Ganciclovir and Drugs Active Against Cytomegalovirus (CMV)
- Oseltamivir and Zanamivir
- Drugs Used in Viral Hepatitis
- Hepatitis C
- Hepatitis B
- 12.3 Antifungal Drugs
- Triazoles
- Imidazoles
- Polyenes
- Other Agents
- 13 Musculoskeletal and metabolic drugs
- 13.1 Calcium and Bone Metabolism
- General Principles
- Bisphosphonates
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions and contraindications
- Adverse effects
- Important interactions
- Examples
- Special requirements
- Calcitonin and Parathyroid Hormones
- Calcitonin
- Parathyroid hormone and related drugs
- Strontium Ranelate
- 13.2 Neuromuscular Drugs
- Skeletal Muscle Relaxants
- Baclofen
- Dantrolene
- Tizanidine
- Anticholinesterases (Acetyl Cholinesterase Inhibitors)
- Pharmacodynamics
- Contraindications
- Cautions
- Adverse effects
- Important interactions
- Examples
- Quinine
- Adverse effects
- Dosing
- 13.3 Gout
- Treatment of Acute Gout
- General principles
- Colchicine
- Pharmacodynamics
- Indications
- Cautions
- Contraindications
- Adverse effects
- Important interactions
- Control of Chronic Gout
- General principles
- Allopurinol
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Contraindications
- Adverse effects
- Important interactions
- 14 Prescribing anticoagulants
- 14.1 Anticoagulation
- Blood Coagulation Cascade
- Warfarin
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Adverse effects
- Important interactions
- Monitoring
- Initiation of treatment
- Rapid anticoagulation
- Slow anticoagulation
- Bridging protocols
- Overdose/overtreatment
- Avoiding prescribing errors
- The Heparins
- General principles and pharmacodynamics
- Low molecular weight heparins
- Pharmacokinetics
- Indications
- Examples
- Unfractionated heparin (UFH)
- Pharmacokinetics
- Indications
- Initiation of treatment and dosing
- Monitoring
- Adverse effects (both UFH and LMWH)
- Fondaparinux
- DIRECT FACTOR Xa INHIBITORS
- Other Anticoagulants
- Direct thrombin inhibitors
- Heparinoids
- 15 Prescribing of fluids
- 15.1 Intravenous Fluids, Infusions and Electrolytes
- Fluid Compartments and Daily Requirements
- Fluid compartments
- Daily fluid and electrolyte requirements
- Formulated Intravenous Fluids
- Crystalloids
- Hypotonic (and relatively hypotonic)
- Isotonic
- Hypertonic
- Colloids
- Fluid Prescribing
- Maintenance fluids
- Fluid replacement
- Resuscitation
- Electrolyte Disturbances
- Potassium
- Hyperkalaemia
- Causes
- Clinical features
- Management
- Hypokalaemia
- Causes
- Clinical features
- Management
- Sodium
- Hypernatraemia (Na+ >150 mmol/L)
- Causes
- Clinical features
- Management
- Hyponatraemia (Na+ <130 mmol/L)
- Causes
- Clinical features
- Management
- Calcium
- Hypercalcaemia (Ca2+ >2.65 mmol/L)
- Causes
- Clinical features
- Management
- Hypocalcaemia (Ca2+ <2.2 mmol/L)
- Causes
- Clinical features
- Management
- Magnesium
- Hypomagnesaemia (Mg2+ <0.7 mmol/L)
- Causes
- Clinical features
- Management
- Phosphate
- Hypophosphataemia (PO43- <0.8 mmol/L)
- Causes
- Clinical features
- Management
- 16 Prescribing in diabetes
- 16.1 Insulin and Prescribing in Diabetes
- Pharmacodynamics
- Types of Insulin
- Quick acting
- Short-acting soluble insulin
- Rapid acting insulin analogues
- Intermediate/long acting
- Isophane insulin
- Long acting insulin analogues (lente insulin)
- Mixed insulins
- Insulin Regimes
- Type 1 diabetes
- Type 2 diabetes
- Insulin and Dose Changes
- High blood sugars
- Low blood sugars
- Avoiding Prescribing Errors
- Insulin Infusions and Sliding Scales
- Fixed rate insulin (diabetic emergencies)
- Diabetic ketoacidosis (DKA)
- Hyperosmolar hyperglycaemic state (HHS)
- Sliding scale regimens
- General principles
- Prescribing
- Hypoglycaemia
- Restarting patients usual insulin/oral hypoglycaemic regimen
- Pre-Operative Patients
- 17 Immunosuppressants
- 17.1 Immunosuppressant and Immunomodulatory Drugs
- Azathioprine and 6-Mercaptopurine (6-MP)
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Contraindications
- Adverse effects
- Important interactions
- Special requirements
- Methotrexate
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Contraindications
- Adverse effects
- Important interactions
- Special requirements
- Sulfasalazine
- Leflunomide Arava®
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Contraindications
- Adverse effects
- Important interactions
- Special requirements
- Ciclosporin
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Contraindications
- Adverse effects
- Important interactions
- Special requirements
- Anti-TNF-α Agents
- Pharmacodynamics
- Pharmacokinetics
- Indications
- Cautions
- Contraindications
- Adverse effects
- Examples
- Special requirements
- 18 Inotropes
- 18.1 Inotropic Drugs (Reference Only)
- Background
- Part III Self-assessment
- 19 Adverse drug reactions
- Case Presentation 1
- Question 1
- Adverse Effect Options
- Case Presentation 2
- Question 2
- Adverse Effect Options
- Case Presentation 3
- Question 3
- Adverse Effect Options
- Case Presentation 4
- Question 4
- Adverse Effect Options
- Case Presentation 5
- Question 5
- Adverse Effect Options
- Case Presentation 6
- Question 6
- Adverse Effect Options
- Case Presentation 7
- Question 7
- Adverse Effect Options
- Case Presentation 8
- Question 8
- Adverse Effect Options
- Answers
- Answer 1: C
- Answer 2: D
- Answer 3: E
- Answer 4: C
- Answer 5: C
- Answer 6: D
- Answer 7: B
- Answer 8: D
- 20 Communicating information
- Case Presentation 1
- Question 1
- Information Options
- Case Presentation 2
- Question 2
- Information Options
- Case Presentation 3
- Question 3
- Information Options
- Case Presentation 4
- Question 4
- Information Options
- Case Presentation 5
- Question 5
- Information Options
- Case Presentation 6
- Question 6
- Information Options
- Answers
- Answer 1: C
- Answer 2: E
- Answer 3: D
- Answer 4: C
- Answer 5: D
- Answer 6: E
- 21 Calculation skills
- Case Presentation 1
- Calculation 1
- Case Presentation 2
- Calculation 2
- Case Presentation 3
- Calculation 3
- Case Presentation 4
- Calculation 4
- Case Presentation 5
- Calculation 5
- Case Presentation 6
- Calculation 6
- Case Presentation 7
- Calculation 7
- Case Presentation 8
- Calculation 8
- Answers
- Workings
- Workings
- Workings
- Workings
- Workings
- Workings
- Workings
- Workings
- 22 Drug monitoring
- Case Presentation 1
- Question 1
- Monitoring Options
- Case Presentation 2
- Question 2
- Monitoring Options
- Case Presentation 3
- Question 3
- Monitoring Options
- Case Presentation 4
- Question 4
- Monitoring Options
- Case Presentation 5
- Question 5
- Monitoring Options
- Case Presentation 6
- Question 6
- Monitoring Options
- Case Presentation 7
- Question 7
- Monitoring Options
- Case Presentation 8
- Question 8
- Monitoring Options
- Answers
- Answer 1: B
- Answer 2: B
- Answer 3: B
- Answer 4: C
- Answer 5: C
- Answer 6: D
- Answer 7: E
- Answer 8: A
- 23 Data interpretation
- Case Presentation 1
- Question 1
- Decision Options
- Case Presentation 2
- Question 2
- Decision Options
- Case Presentation 3
- Question 3
- Decision Options
- Case Presentation 4
- Question 4
- Decision Options
- Case Presentation 5
- Question 5
- Decision Options
- Case Presentation 6
- Question 6
- Decision Options
- Answers
- Answer 1: D
- Answer 2: A
- Answer 3: E
- Answer 4: D
- Answer 5: E
- Answer 6: C
- 24 Planning management
- Case Presentation 1
- Question 1
- Management Options
- Case Presentation 2
- Question 2
- Management Options
- Case Presentation 3
- Question 3
- Management Options
- Case Presentation 4
- Question 4
- Management Options
- Answers
- Answer 1: D
- Answer 2: C
- Answer 3: A
- Answer 4: B
- 25 Prescription review
- Case Presentation 1
- Current Prescriptions
- Question 1A
- Question 1B
- Case Presentaion 2
- Current Prescriptions
- Question 2A
- Question 2B
- Case Presentation 3
- Current Prescriptions
- Question 3A
- Question 3B
- Case Presentation 4
- Current Prescriptions
- Question 4A
- Question 4B
- Question 4C
- Case Presentation 5
- Current Prescriptions
- Question 5A
- Case Presentation 6
- Current Prescriptions
- Question 6A
- Question 6B
- Case Presentation 7
- Current Medications
- Question 7A
- Question 7B
- Case Presentation 8
- Current Medications
- Question 8A
- Question 8B
- Answers
- Answer 1A: C
- Answer 1B: D, E, H
- Answer 2A: B, E
- Answer 2B: A, D
- Answer 3A: F, G
- Answer 3B: C
- Answer 4A: J
- Answer 4B: E, H
- Answer 4C: G
- Answer 5A: C, D, F, G, H
- Answer 6A: B, E
- Answer 6B: A, F
- Answer 7A: F, G
- Answer 7B: B, E
- Answer 8A: A, C
- Answer 8B: F, G
- 26 Prescribing
- Questions
- Background
- Question Information
- Scenario 1
- Scenario 2
- Scenario 3
- Scenario 4
- Scenario 5
- Scenario 6
- Scenario 7
- Scenario 8
- Answers
- Scenario 1
- Scenario 2
- Scenario 3
- Scenario 4
- Scenario 5
- Scenario 6
- Scenario 7
- Scenario 8
- Index