Brody's Human Pharmacology
Kaup valmöguleikar
Brody’s Human Pharmacology is a well-established and much-loved textbook that guides students of medicine, pharmacology and other health professions through pharmacology from both basic and clinical perspectives. What can be a very difficult and complex topic is divided into easily digestible chapters, each of which is clearly structured from a therapeutic overview to mechanisms of action, relationships to clinical responses, pharmacokinetics, pharmacovigilance, new developments, and clinical relevance for all health professionals.
Contains all the essential aspects of pharmacology – suitable for exam preparation Full color illustrations explain important processes and color-coded boxes enhance understanding Therapeutic overviews, clinical problems and trade names – everything you need to know Self-assessment questions and further reading to reinforce learning Current developments for each class of drugs and how information relates to students in the healthcare professions bring learning to life Updated content throughout Pharmacodynamics chapter revised to include discussions of positive and negative allosteric modulators, as well as biased agonism Pharmacogenetics chapter considers genetic variations and their relationship to drug responses Section on cancer drugs revised to reflect major advances New chapter on immunological and cell-based therapies.
Nánar um bókina
- Elsevier Limited (UK)
- 9780323846745
- 9780323846738
- ePub
- 7
- Lynn Wecker, Susan L. Ingram
- English
- 2024-02-02
- 10
Kaflar
- Cover image
- Title page
- Table of Contents
- Any screen, Any time, Anywhere
- Copyright
- Contributors
- Preface
- Dedication and Acknowledgments
- List of Tables
- Section 1: Mechanisms of Drug Action and Therapeutic Principles
- Chapter 1: Introduction
- Website
- Chapter 2: Cellular Receptors and Drug Concentration–Response Relationships
- Biological Sites and Specificity of Drug Action
- General Properties of Cellular Receptors
- Agonists and Antagonists
- Receptor Families, Subtypes, and Signaling Cascades
- Quantitative Relationships
- Self-Assessment Questions
- Website
- Chapter 3: Pharmacokinetics
- Absorption and Distribution
- Metabolism and Elimination of Drugs
- Clinical Considerations
- Calculation of Pharmacokinetic Parameters
- Multiple or Prolonged Dosing
- Pharmacogenomics
- Special Populations and Disease Considerations
- Biologics
- Summary
- Self-Assessment Questions
- Chapter 4: Pharmacogenetics
- Genes Affecting Pharmacokinetics: Drug Metabolism and Drug Transporters
- Genes Affecting Pharmacodynamics
- Cancer Pharmacogenetics
- Summary
- Self-Assessment Questions
- Websites
- Chapter 5: Drug Discovery, Development, and Regulation
- Introduction
- Drug Discovery and Development
- Prescription Writing and Regulation
- Summary
- Terms
- Self-Assessment Questions
- Websites
- Section 2: Chemical Mediators and Drugs Affecting Autonomic and Neuromuscular Synapses
- Chapter 6: Introduction to the Autonomic Nervous System
- Divisions of the Autonomic Nervous System
- Control of the Autonomic Nervous System
- Functional Responses Mediated by the Autonomic Nervous System
- Neurotransmission in the Autonomic Nervous System
- Neurotransmitters in the Autonomic Nervous System
- Neurotransmitter Receptors in the Autonomic Nervous System
- Drugs Affecting the Autonomic Nervous System
- New Developments
- Self-Assessment Questions
- Websites
- Cholinergic Drugs
- Chapter 7: Muscarinic Agonists, Cholinesterase Inhibitors, and Their Clinical Uses
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 8: Muscarinic Antagonists and Their Clinical Uses
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Website
- Chapter 9: Nicotinic Agonists and Their Clinical Uses
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- Clinical Relevance for Healthcare Professionals
- New Developments
- Self-Assessment Questions
- Website
- Chapter 10: Neuromuscular Blocking Drugs and Nicotinic Antagonists
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Website
- Adrenergic Drugs
- Chapter 11: Adrenergic Agonists and Their Clinical Uses
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 12: Adrenergic Antagonists and Their Clinical Uses
- Therapeutic Overview
- Mechanisms of Action
- Mixed-Action β1-Adrenergic Receptor Antagonist and β3-Adrenergic Receptor Agonist
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Section 3: Drug Treatment for Disorders Affecting the Central Nervous System
- Chapter 13: The Central Nervous System
- Introduction
- Neurotransmission in the Central Nervous System
- Organization of the Central Nervous System
- Drug Action in the Central Nervous System
- Self-Assessment Questions
- Website
- Chapter 14: Drug Therapy for Alzheimer Disease and Other Cognitive Disorders/Dementias
- Therapeutic Overview
- Pathophysiology
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 15: Pharmacotherapy of Basal Ganglia Disorders: Parkinson Disease and Huntington Disease
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 16: Drug Therapy for Psychoses and Bipolar Disorder
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 17: Drug Therapy for Depression and Anxiety
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 18: Drug Therapy for the Management of Attention Deficit-Hyperactivity Disorder
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- Drug Use Disorder and Dependence
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 19: Drug Therapy for Insomnia and the Hypersomnias
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 20: Drug Therapy for Managing Obesity and Eating Disorders
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 21: Treatment of Seizure Disorders
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 22: Drug Therapy for Spasticity Disorders
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 23: Ethanol, Other Alcohols, and Medications for Alcohol Use Disorder
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Chapter 24: Psychoactive Compounds and Substance Use Disorder
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Section 4: Drug Therapy for Pain Management
- Chapter 25: Introduction
- Neurophysiology of Pain
- Specific Pain Syndromes
- Website
- Chapter 26: General Anesthetics
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Website
- Chapter 27: Local Anesthetics
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Practitioners
- Self-Assessment Questions
- Websites
- Chapter 28: Opioid Analgesics
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 29: Nonsteroidal Antiinflammatory Drugs and Acetaminophen
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 30: Cannabinoids
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Website
- Chapter 31: Drug Therapy for Migraine Headache
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Section 5: Treatment of Inflammatory, Allergic and Immunologic Disorders
- Chapter 32: Drug Therapy for Gout and Hyperuricemia
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Chapter 33: Pharmacological Interventions for Allergic Reactions
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Chapter 34: Immunosuppressants for Autoimmune Disorders and Organ Transplantation
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Chapter 35: Drug Therapy for Rheumatoid Arthritis
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Section 6: Drug Treatment for Cardiovascular Diseases
- Chapter 36: Introduction to the Regulation of Cardiovascular Function
- Central Control of Autonomic Nerve Activity
- Regulation of Sympathetic Activity
- Self-Assessment Questions
- Websites
- Chapter 37: Overview of Hypertension Management and Drugs That Decrease Sympathetic Tone
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Chapter 38: Diuretics and Drugs That Affect Volume and Electrolyte Content
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Website
- Chapter 39: Drugs Affecting the Renin-Angiotensin-Aldosterone System
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 40: Calcium-Channel Blockers
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 41: Vasodilators for Hypertensive Crises, Pulmonary Hypertension, and Erectile Dysfunction
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Chapter 42: Treatment of Hyperlipidemias and Atherosclerotic Cardiovascular Disease
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Chapter 43: Treatment of Myocardial Ischemia and Angina Pectoris
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Chapter 44: Treatment of Heart Failure
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Chapter 45: Antiarrhythmic Drugs
- Therapeutic Overview
- Cardiac Electrophysiology
- Mechanisms of Action of Antiarrhythmic Drugs
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Chapter 46: Anticoagulant, Antiplatelet, and Fibrinolytic Medications
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 47: Drug Therapy for Hemophilia and the Deficiency Anemias
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Section 7: Treatment of Endocrine Disorders
- Chapter 48: Introduction to Endocrine Pharmacology
- Introduction
- Hormones
- New Developments
- Clinical Relevance for Healthcare Professionals
- Chapter 49: Treatment of Hypothalamic and Pituitary Disorders
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 50: Diagnosis and Treatment of Adrenocorticosteroid Disorders
- Therapeutic Overview
- Mechanisms of Action
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 51: Female Hormone Regulation
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 52: Androgens, Antiandrogens, and Their Clinical Uses
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Website
- Chapter 53: Drug Therapy for the Management of Diabetes
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 54: Drug Therapy for the Management of Thyroid Disorders
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Website
- Chapter 55: Calcium Regulating Hormones and Other Agents Affecting Bone
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Section 8: Chemotherapy
- Infectious Diseases
- Chapter 56: Principles of Antimicrobial Use
- Introduction
- Drug-Bacteria Interactions
- Host-Bacteria Interactions
- Drug-Host Interactions
- Antimicrobial Therapy
- Self-Assessment Questions
- Websites
- Chapter 57: Drugs Targeting Bacterial Cell Walls and Membranes
- Therapeutic Overview
- Mechanisms of Action
- Mechanisms of Resistance
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 58: Drugs Targeting Bacterial Protein Synthesis
- Therapeutic Overview
- Mechanisms of Action
- Mechanisms of Resistance
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Website
- Chapter 59: Drugs Targeting Bacterial DNA
- Therapeutic Overview
- Mechanisms of Action
- Mechanisms of Resistance
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 60: Antimycobacterial Agents
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 61: Drugs Targeting Resistant Organisms
- Therapeutic Overview
- Multidrug-Resistant Gram-Positive Bacteria
- Multidrug-Resistant Gram-Negative Bacteria
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Parasitic Diseases
- Chapter 62: Antifungal Agents
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Website
- Chapter 63: Antimalarial and Other Antiprotozoal Agents
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 64: Anthelmintics and Ectoparasiticides
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Viruses
- Chapter 65: Antiviral Agents
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 66: Antiretroviral Drugs for HIV
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Cancer
- Chapter 67: Principles of Cancer and Antineoplastic Drug Use
- Overview
- Cancer in the Clinic
- Biology of Cancer
- Treatment of Cancer
- Common Problems in the Treatment of Cancer
- New Developments
- Self-Assessment Questions
- Websites
- Chapter 68: Cytotoxic Agents
- Therapeutic Overview
- Mechanisms of Action
- Mechanisms of Resistance
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 69: Targeted Anticancer Agents
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 70: Immunological and Cell-Based Therapies
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Section 9: Special Considerations
- Chapter 71: Therapeutic Use of Hematopoietic Growth Factors
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 72: Gastrointestinal Disorders and Their Treatment
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 73: Pharmacological Interventions for Asthma and Chronic Obstructive Pulmonary Disorders
- Therapeutic Overview
- Mechanisms of Action
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacokinetics
- Pharmacovigilance: Adverse Effects and Drug Interactions
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 74: Dietary Supplements, Nutraceuticals, and Natural Products
- Therapeutic Overview
- Mechanisms of Action
- Pharmacokinetics
- Relationship of Mechanisms of Action to Clinical Response
- Pharmacovigilance: Side Effects, Clinical Problems, and Toxicity
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 75: Essentials of Toxicology
- Toxicology Overview
- Mechanisms of Action
- Toxicant Interactions
- Emerging Issues
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Chapter 76: Therapeutic Considerations for Pregnant, Pediatric, Geriatric, and Obese Individuals
- Therapeutic Overview
- Relationship of Population Characteristics to Drug Responses
- New Developments
- Clinical Relevance for Healthcare Professionals
- Self-Assessment Questions
- Websites
- Appendix
- Index
- Confidence is ClinicalKey