Applied Pathophysiology for the Advanced Practice Nurse
Höfundar:
Lucie Dlugasch; Lachel Story (Útgáfa: 2)
Kaup valmöguleikar
Applied Pathophysiology for the Advanced Practice Nurse, Second Edition is a comprehensive resource that serves as a bridge between clinical experience and the advanced knowledge necessary for the role of an APRN. It helps graduate students navigate the data and presentation of symptoms that must be considered when making a diagnosis and recommendation for treatment. This unique text includes expanded pathophysiology content across the life span and information to meet the needs of many advanced practice population areas, including pediatrics, psychiatric mental health, and gerontology.
It also incorporates information from both an acute and primary care focus. The Second Edition was thoroughly updated to offer the latest information and data, including a new section on microbiology and infectious diseases with information on COVID-19, a new section on the endocannabinoid system, new information on genetic testing principles, several newly added psychiatric mental health disorders, and more timely topics.
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- Jones & Bartlett Learning
- 9781284255638
- 9781284255614
- ePub
- 2
- Lucie Dlugasch; Lachel Story
- English
- 2023-03-16
- 100
Kaflar
- Cover
- Title Page
- Copyright Page
- Brief Contents
- Diagnostic Links
- Contents
- Preface
- New to this Edition
- Contributors
- Acknowledgments
- CHAPTER 1 Cellular Function
- Basic Cell Function and Structure
- Cellular Components
- Exchanging Material
- Energy Production
- Chromosomes, DNA, and Genes
- Replication and Differentiation
- Cellular Organization
- Types of Tissue
- Cellular Adaptation and Damage
- Cellular Adaptation
- Cellular Injury and Death
- Genetic and Epigenetic Alterations
- Benign and Malignant Neoplasms
- Genetic and Congenital Disorders
- Patterns of Inheritance
- Single-Gene Disorders
- Chromosomal Disorders—Number or Structural
- Autosomal Aneuploidy
- X-Linked Aneuploidy
- Chromosomal Structural Disorders
- Multifactorial Disorders
- Chapter Summary
- References and Resources
- CHAPTER 2 Immunity
- Innate Immunity
- Barriers
- Inflammatory Response
- Adaptive Immunity
- Cellular Immunity
- Humoral Immunity
- Immune Changes Across the Life Span
- Infectious Disorders
- Bacteria
- Fungi
- Protozoa
- Helminths
- Viruses and Prions
- Vaccines
- Altered Immune Response
- Hypersensitivity
- Hypersensitivity by Mechanism
- Hypersensitivity by Antigen
- Immunodeficiency
- Developing a Strong Immune System
- Chapter Summary
- References and Resources
- CHAPTER 3 Hematopoietic Function
- Hematopoietic System
- Hematopoiesis
- Hemostasis
- Lymphoid System
- Understanding Conditions That Affect The Hematopoietic System
- Diseases of the White Blood Cells
- Neutrophils
- Eosinophils and Basophils
- Lymphocytes and Monocytes
- Lymphomas
- Myelodysplastic Syndrome
- Leukemias
- Diseases of the Red Blood Cells
- Anemia
- Polycythemia
- Iron Overload
- Diseases of the Platelets
- Thrombocytopenia
- Thrombocythemia
- Diseases of Coagulation or Hemostasis
- Hemophilia
- Von Willebrand Disease
- Disseminated Intravascular Coagulation
- Thrombophilia
- Chapter Summary
- References and Resources
- CHAPTER 4 Cardiovascular Function
- Anatomy and Physiology
- Heart
- Cardiac Cycle
- Conduction System
- Blood Vessels
- Blood Pressure and Cardiac Output
- Lymphatic System
- Understanding Conditions That Affect the Cardiovascular System
- Impaired Cardiac Output: Heart Disease
- Pericarditis
- Infective Endocarditis
- Myocarditis
- Valvular Disorders
- Cardiomyopathy
- Electrical Alterations
- Heart Failure
- Congenital Heart Defects
- Impaired Tissue Perfusion: Vascular Disorders
- Arterial Disorders
- Arterial and Venous Disorders
- Venous Disorders
- Lymphedema
- Conditions Resulting in Decreased Cardiac Output and Altered Perfusion
- Hypertension
- Shock
- Chapter Summary
- References and Resources
- CHAPTER 5 Pulmonary Function
- Anatomy and Physiology
- Ventilation
- Respiration
- Neural Regulation, Lung Volume, and Lung Capacity
- Understanding Conditions That Affect the Pulmonary System
- Infectious Disorders
- Upper Respiratory Tract Infections
- Lower Respiratory Tract Infections
- Alterations in Ventilation
- Asthma—Obstructive
- Chronic Obstructive Pulmonary Disease
- Sleep Apnea—Obstructive
- Cystic Fibrosis—Obstructive
- Lung Cancer
- Pleural Effusion
- Effusions
- Pneumothorax
- Acute Respiratory Distress Syndrome—Restrictive
- Alterations in Ventilation and Perfusion
- Atelectasis—Restrictive
- Acute Respiratory Failure
- Chapter Summary
- References and Resources
- CHAPTER 6 Fluid, Electrolyte, and Acid–Base Homeostasis
- Fluid and Electrolyte Balance
- Distribution
- Fluid Movement
- Fluid Regulation
- Electrolytes
- Fluid and Electrolyte Imbalances
- Sodium and Water
- Fluid Excess
- Fluid Deficit
- Hypernatremia
- Hyponatremia
- Chloride
- Potassium
- Calcium
- Phosphorus
- Magnesium
- Acid–Base Balance
- pH Regulation
- Buffers
- Respiratory Regulation
- Renal Regulation
- Compensation
- Metabolic Acidosis
- Metabolic Alkalosis
- Respiratory Acidosis
- Respiratory Alkalosis
- Mixed Disorders
- Arterial Blood Gas Interpretation
- Practice Arterial Blood Gas Interpretation
- Chapter Summary
- References and Resources
- CHAPTER 7 Urinary Function
- Anatomy and Physiology
- Structure
- Urine Formation
- Urine Elimination
- Understanding Conditions That Affect the Urinary System
- Conditions Resulting in Altered Urinary Elimination
- Incontinence
- Neurogenic Bladder
- Bladder Pain Syndrome/Interstitial Cystitis
- Congenital Disorders
- Urinary Tract Infections
- Urinary Tract Obstructions
- Tumors and Cysts
- Benign Prostatic Hyperplasia
- Prostate Cancer
- Conditions Resulting in Impaired Renal Function
- Polycystic Kidney Disease
- Glomerular Disorders
- Kidney Injury and Disease
- Chapter Summary
- References and Resources
- CHAPTER 8 Reproductive Function
- Anatomy and Physiology
- Normal Male Reproductive System
- Normal Female Reproductive System
- Understanding Conditions That Affect the Reproductive System
- Congenital Disorders
- Epispadias
- Hypospadias
- Cryptorchidism
- Infertility Issues
- Disorders of the Penis
- Erectile Dysfunction
- Phimosis and Paraphimosis
- Priapism
- Disorders of the Testes and Scrotum
- Hydrocele
- Spermatocele
- Varicocele
- Testicular Torsion
- Disorders of Pelvic Support
- Menstrual Disorders
- Abnormal Uterine Bleeding
- Amenorrhea
- Heavy and Intermenstrual Bleeding
- Dysmenorrhea
- Premenstrual Syndrome
- Disorders of the Uterus
- Endometriosis
- Leiomyomas
- Disorders of the Ovaries
- Ovarian Cysts
- Polycystic Ovary Syndrome
- Disorders of the Breasts
- Benign Breast Masses
- Mastitis
- Reproductive Tract Infections
- Prostatitis
- Epididymitis
- Candidiasis
- Sexually Transmitted Infections
- Bacterial STIs
- Viral STIs
- Protozoan STIs
- Cancers
- Penile Cancer
- Testicular Cancer
- Breast Cancer
- Cervical Cancer
- Endometrial Cancer and Uterine Sarcoma
- Ovarian Cancer
- Chapter Summary
- References and Resources
- CHAPTER 9 Gastrointestinal Function
- Anatomy and Physiology
- Upper Gastrointestinal Tract
- Lower Gastrointestinal Tract
- Liver
- Pancreas
- Gastrointestinal Changes Associated with Aging
- Understanding Conditions That Affect the Gastrointestinal System
- Disorders of the Upper Gastrointestinal Tract and Accessory Organs
- Congenital Defects
- Cleft Lip and Cleft Palate
- Esophageal Atresia
- Pyloric Stenosis
- Dysphagia
- Vomiting
- Hiatal Hernia
- Gastroesophageal Reflux Disease
- Gastritis
- Peptic Ulcers
- Cholelithiasis
- Disorders of the Liver
- Hepatitis
- Cirrhosis
- Nonalcoholic Fatty Liver Disease
- Disorders of the Pancreas
- Pancreatitis
- Disorders of the Lower Gastrointestinal Tract
- Diarrhea
- Constipation
- Intestinal Obstruction
- Appendicitis
- Peritonitis
- Celiac Disease
- Inflammatory Bowel Disease
- Irritable Bowel Syndrome
- Diverticular Disease
- Cancers
- Oral Cancer
- Esophageal Cancer
- Gastric Cancer
- Liver Cancer
- Pancreatic Cancer
- Colorectal Cancer
- Chapter Summary
- References and Resources
- CHAPTER 10 Endocrine Function
- Anatomy and Physiology
- Hormonal Regulation
- Pituitary Gland and Hypothalamus
- Pancreas
- Thyroid Gland
- Parathyroid Glands
- Adrenal Glands
- Understanding Conditions That Affect the Endocrine System 512
- Disorders of the Pituitary Gland
- Hypopituitarism
- Hyperpituitarism
- Prolactin Disorders: Prolactinemia
- Growth Hormone Disorders
- Antidiuretic Hormone (Vasopressin) Disorders
- Diabetes Mellitus
- Type 1 Diabetes
- Monogenic Diabetes
- Type 2 Diabetes
- Gestational Diabetes
- Metabolic Syndrome
- Obesity
- Disorders of the Thyroid Gland
- Goiter and Thyroid Nodules
- Hypothyroidism
- Hyperthyroidism
- Disorders of the Parathyroid Glands
- Hypoparathyroidism
- Hyperparathyroidism
- Disorders of the Adrenal Glands
- Pheochromocytoma
- Cushing Syndrome
- Adrenal Insufficiency
- Chapter Summary
- References and Resources
- CHAPTER 11 Neural Function
- Anatomy and Physiology
- Central Nervous System
- Peripheral Nervous System
- Autonomic Nervous System
- Blood Supply to the CNS
- Understanding Conditions That Affect the Nervous System 563
- Congenital Neurologic Disorders
- Hydrocephalus
- Spina Bifida
- Cerebral Palsy
- Infectious Neurologic Disorders
- Meningitis
- Encephalitis
- Zika Virus Disease
- Traumatic Neurologic Disorders
- Traumatic Brain Injuries
- Increased Intracranial Pressure
- Hematomas
- Spinal Cord Injuries
- Vascular Neurologic Disorders
- Cerebrovascular Accident
- Cerebral Aneurysm
- Arteriovenous Malformations
- Headache Disorders
- Migraine Headaches
- Tension-Type Headaches
- Cluster Headaches
- Seizure Disorders
- Chronic Degenerative Disorders
- Multiple Sclerosis
- Parkinson Disease
- Amyotrophic Lateral Sclerosis
- Myasthenia Gravis
- Huntington Disease
- Dementia
- Alzheimer Disease
- Vascular Dementia
- Dementia With Lewy Bodies
- Frontotemporal Dementia
- Creutzfeldt-Jakob Disease
- AIDS Dementia Complex
- Cancers of the Nervous System
- Brain Tumors
- Mental Health Disorders
- Neurodevelopmental Disorders
- Personality Disorders
- Substance Use Disorders
- Feeding and Eating Disorders
- Unipolar Depressive Disorders
- Bipolar Disorders
- Schizophrenia
- Anxiety Disorders
- Obsessive-Compulsive Disorders
- Chapter Summary
- References and Resources
- CHAPTER 12 Musculoskeletal Function
- Anatomy and Physiology
- Bones
- Bone Remodeling
- Joints
- Muscles
- Musculoskeletal Changes Associated with Aging
- Understanding Conditions That Affect the Musculoskeletal System
- Congenital and Developmental Musculoskeletal Disorders
- Developmental Hip Dysplasia
- Osteogenesis Imperfecta
- Spinal Deviations
- Traumatic Musculoskeletal Disorders
- Fractures
- Dislocations
- Sprains
- Strains
- Bursitis
- Anatomic-Specific Injuries
- Low Back Pain
- Metabolic Bone Disorders
- Osteoporosis
- Rickets and Osteomalacia
- Paget Disease
- Inflammatory Joint Disorders
- Osteoarthritis
- Rheumatoid Arthritis
- Juvenile Idiopathic Arthritis
- Gout
- Ankylosing Spondylitis
- Chronic Muscle Disorders
- Muscular Dystrophy
- Fibromyalgia
- Bone and Muscle Neoplasms
- Chapter Summary
- References and Resources
- CHAPTER 13 Integumentary Function
- Anatomy and Physiology
- Epidermis
- Dermis and Appendages
- Subcutaneous Tissue
- Nails
- Understanding Conditions That Affect the Integumentary System 694
- Congenital Integumentary Disorders
- Birthmarks
- Disorders of Melanin
- Integumentary Changes Associated with Aging
- Inflammatory Integumentary Disorders
- Contact Dermatitis
- Atopic Dermatitis
- Urticaria
- Psoriasis
- Infectious Integumentary Disorders
- Bacterial Infections
- Viral Infections
- Parasitic Infections
- Traumatic Integumentary Disorders
- Burns
- Pressure Injuries
- Chronic Integumentary Disorders
- Acne Vulgaris
- Rosacea
- Integumentary Cancers
- Hair Disorders
- Nail Disorders
- Chapter Summary
- References and Resources
- CHAPTER 14 Sensory Function
- Anatomy and Physiology
- Eyes
- Ears
- Understanding Conditions That Affect the Senses
- Pain
- Pain Mechanisms
- Pain Transmission
- Types of Pain
- Congenital Sensory Disorders
- Eyes
- Ears
- Sensory Conditions Associated with Aging
- Eyes
- Ears
- Infectious and Inflammatory Sensory Disorders
- Eyes
- Ears
- Traumatic Sensory Disorders
- Eyes
- Ears
- Chronic Sensory Disorders
- Eyes
- Ears
- Sensory Organ Cancers
- Eyes
- Miscellaneous Sensory Organ Conditions
- Eyes
- Ears
- Chapter Summary
- References and Resources
- Glossary
- Index